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SNX17 antibody (AA 280-457)

SNX17 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7170364
  • Target See all SNX17 Antibodies
    SNX17 (Sorting Nexin 17 (SNX17))
    Binding Specificity
    • 10
    • 9
    • 7
    • 5
    • 3
    • 1
    AA 280-457
    Reactivity
    • 28
    • 3
    • 2
    Human
    Host
    • 24
    • 4
    Rabbit
    Clonality
    • 26
    • 2
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This SNX17 antibody is un-conjugated
    Application
    • 24
    • 18
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Sorting nexin-17 protein (280-457AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SNX17 (Sorting Nexin 17 (SNX17))
    Alternative Name
    SNX17 (SNX17 Products)
    Synonyms
    snx17 antibody, MGC53167 antibody, MGC69341 antibody, MGC198061 antibody, MGC83142 antibody, SNX17 antibody, wu:fb67g03 antibody, wu:fb67g09 antibody, wu:fc27g08 antibody, wu:fj81d04 antibody, si:ch211-101l18.2 antibody, 5830447M19Rik antibody, AI790646 antibody, D5Ertd260e antibody, mKIAA0064 antibody, sorting nexin 17 antibody, sorting nexin 17 L homeolog antibody, snx17 antibody, SNX17 antibody, snx17.L antibody, Snx17 antibody
    Background

    Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

    Aliases: Similar to a putative C elegans gene encoded in cosmid F17H10 antibody, Snx17 antibody, SNX17_HUMAN antibody, Sorting nexin 17 antibody, Sorting nexin-17 antibody

    UniProt
    Q15036
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