Taste Receptor, Type 2, Member 7 (TAS2R7) (C-Term), (AA 207-235) antibody

Details for Product No. ABIN955085
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Antigen
Synonyms t2r1, t2r7, trb4, T2R7, Tas2r13, Tas2r7, STC74, T2R30, Tas2r30, mt2r42, TRB4, Patr-T2R7
Epitope
C-Term, AA 207-235
(8), (7), (5), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(47), (2), (2)
Host
Rabbit
(49)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(31), (20), (16), (9), (7), (6), (3), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN955085
357.50 $
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Immunogen KLH conjugated synthetic peptide between 207-235 amino acids from the C-terminal region of human TAS2R7
Specificity This antibody reacts to TAS2R7.
Purification Affinity chromatography on Protein A
Alternative Name TAS2R7
Background This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Alternate names: TRB4, Taste receptor family B member 4, Taste receptor type 2 member 7
Gene ID 50837
NCBI Accession NP_076408
Research Area Neurology
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Margolskee: "Molecular mechanisms of bitter and sweet taste transduction." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 1-4, 2002 (PubMed).

Montmayeur, Matsunami: "Receptors for bitter and sweet taste." in: Current opinion in neurobiology, Vol. 12, Issue 4, pp. 366-71, 2002 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Go, Satta, Takenaka et al.: "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates." in: Genetics, Vol. 170, Issue 1, pp. 313-26, 2005 (PubMed).

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