TBC1D3E (C-Term), (AA 497-527) antibody

Details for Product No. ABIN955097
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Antigen
Epitope
C-Term, AA 497-527
(2), (2)
Reactivity
Human
(2)
Host
Rabbit
(2)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(2)
Pubmed 5 references available
Catalog no. ABIN955097
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 497-527 amino acids from the C-terminal region of human TBC1D3E
Specificity This antibody reacts to TBC1D3E.
Purification Affinity chromatography on Protein A
Background BC1D3E acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Alternate names: TBC1 domain family member 3E/3F
Gene ID 84218
NCBI Accession NP_115634
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Paulding, Ruvolo, Haber: "The Tre2 (USP6) oncogene is a hominoid-specific gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2507-11, 2003 (PubMed).

Zody, Garber, Adams et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage...." in: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006 (PubMed).

Hodzic, Kong, Wainszelbaum et al.: "TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12." in: Genomics, Vol. 88, Issue 6, pp. 731-6, 2006 (PubMed).

Wainszelbaum, Charron, Kong et al.: "The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking." in: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 13233-42, 2008 (PubMed).

Alkan, Kidd, Marques-Bonet et al.: "Personalized copy number and segmental duplication maps using next-generation sequencing." in: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009 (PubMed).

Hosts (2)
Reactivities (2)
Applications (2)
Epitopes (2), (2)
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