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THEMIS antibody (Thymocyte Selection Associated) (AA 566-595)

Details for Product anti-THEMIS Antibody No. ABIN955183, Supplier: Log in to see
Antigen
  • A430108D01
  • bA325O24.3
  • bA325O24.4
  • BB160712
  • C6orf190
  • C6orf207
  • C9H6ORF190
  • E430004N04Rik
  • GASP
  • Gasp
  • im:7138580
  • SPOT
  • thylex
  • tsepa
  • Tsepa
  • TSEPA
Epitope
AA 566-595, C-Term
27
15
5
1
1
Reactivity
Human, Mouse (Murine)
42
27
13
Host
Rabbit
35
12
4
3
1
Clonality
Polyclonal
Conjugate
This THEMIS antibody is un-conjugated
5
4
4
4
3
3
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
42
26
14
11
5
4
2
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS
Isotype Ig
Specificity This antibody detects THEMIS (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name THEMIS (THEMIS Antibody Abstract)
Background This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.Synonyms: C6orf190, C6orf207, Protein
Gene ID 387357
NCBI Accession NP_001010923
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-THEMIS antibody (Thymocyte Selection Associated) (AA 566-595) (ABIN955183) THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin...
Western Blotting (WB) image for anti-THEMIS antibody (Thymocyte Selection Associated) (AA 566-595) (ABIN955183) THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35 µg/l...
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010

Bhatti, Doody, Rajaraman, Alexander, Yeager, Hutchinson, Burdette, Thomas, Hunter, Simon, Weinstock, Rosenstein, Stovall, Preston, Linet, Hoover, Chanock, Sigurdson: "Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists." in: Radiation research, Vol. 173, Issue 2, pp. 214-24, 2010

Patrick, Oda, Hayakawa, Sato, Eshima, Kirikae, Iemura, Shirai, Abe, Natsume, Sasazuki, Suzuki: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, 2009

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009