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Thymocyte Selection Associated (THEMIS) (C-Term), (AA 566-595) antibody

Details for Product No. ABIN955183
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Antigen
Synonyms C6orf190, C6orf207, GASP, SPOT, TSEPA, bA325O24.3, bA325O24.4, C9H6ORF190, A430108D01, BB160712, E430004N04Rik, Gasp, Tsepa, thylex, tsepa, im:7138580
Epitope
C-Term, AA 566-595
(10), (7), (2)
Reactivity
Human, Mouse (Murine)
(23), (17), (12), (12), (12)
Host
Rabbit
(25), (3), (1), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(19), (13), (10), (6), (4), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN955183
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS
Specificity This antibody detects THEMIS (C-term).
Purification Protein A column followed by peptide affinity purification
Alternative Name THEMIS
Background This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T- cells. Alternative splicing results in multiple transcript variants.
Alternate names: C6orf190, C6orf207, Protein
Gene ID 387357
NCBI Accession NP_001010923
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Patrick, Oda, Hayakawa et al.: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bhatti, Doody, Rajaraman et al.: "Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists." in: Radiation research, Vol. 173, Issue 2, pp. 214-24, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN955183
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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