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Thyroperoxidase antibody (Internal Region)

TPO Reactivity: Human WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN955202
  • Target See all Thyroperoxidase (TPO) Antibodies
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 57
    • 25
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 25
    • 3
    Goat
    Clonality
    • 46
    • 21
    Polyclonal
    Conjugate
    • 29
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Thyroperoxidase antibody is un-conjugated
    Application
    • 52
    • 29
    • 14
    • 13
    • 13
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    C-TRHVIQVSNE VVTDD
    Specificity
    This antibody is expected to recognize reported isoforms a (NP_000538.3) and e (NP_783653.1).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_000538.3, NP_783650.1, NP_783652.1, NP_783653.1.
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Abstract
    TPO Products
    Synonyms
    MSA antibody, TDH2A antibody, TPX antibody, TPO antibody, msa antibody, tpx antibody, xtpo antibody, LOC100218312 antibody, thyroid peroxidase antibody, TPO antibody, Tpo antibody, tpo antibody, LOC100547103 antibody
    Background
    Thyroid peroxidase (TPO) is an enzyme expressed in the thyroid gland which is necessary for the production of thyroid hormes such as thyroxine. Congenital hypothyroidism and congenital goiter are both associated with mutations in the TPO gene.
    Gene ID
    7173
    NCBI Accession
    NP_000538
    Pathways
    Thyroid Hormone Synthesis
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