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NKX2-1 antibody (N-Term)
NKX2-1
Reactivity: Human
WB, FACS, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NKX2-1 Antibody
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Target
See all NKX2-1 Antibodies
NKX2-1
(NK2 Homeobox 1 (NKX2-1))
Binding Specificity
All epitopes for NKX2-1 antibodies
AA 1-30, N-Term
Reactivity
All reactivities for NKX2-1 antibodies
Human
Host
All hosts for NKX2-1 antibodies
Rabbit
Clonality
All clonalities for NKX2-1 antibodies
Polyclonal
Conjugate
All conjugates for NKX2-1 antibodies
This NKX2-1 antibody is un-conjugated
Application
All applications for NKX2-1 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes human TTF1 / NKX2A at N-term.
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human NKX2-1
Isotype
Ig Fraction
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Discover our top product NKX2-1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NKX2-1
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Target
NKX2-1
(NK2 Homeobox 1 (NKX2-1))
Alternative Name
TTF1 / NKX2A (NKX2-1 Products )
Synonyms
BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
Background
The NKX2-1 gene encodes a protein initially identified as a thyroid-specific transcription factor (TTF). TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NKX2-1, Nkx-2.1, TITF1, TTF-1, Thyroid nuclear factor 1, Thyroid transcription factor 1
Molecular Weight
38596 Da
Gene ID
7080
NCBI Accession
NP_001073136
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Systemic Arterial Blood Pressure by Hormones , Cellular Glucan Metabolic Process , Feeding Behaviour
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