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TIM3 antibody
TIM 3
Reactivity: Mouse
FACS, IHC (fro)
Host: Rat
Monoclonal
25F-1D6
unconjugated
Product Details anti-TIM3 Antibody
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Target
See all TIM3 (TIM 3) Antibodies
TIM3 (TIM 3)
(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
Reactivity
All reactivities for TIM3 antibodies
Mouse
Host
All hosts for TIM3 antibodies
Rat
Clonality
All clonalities for TIM3 antibodies
Monoclonal
Conjugate
All conjugates for TIM3 antibodies
This TIM3 antibody is un-conjugated
Application
All applications for TIM3 antibodies
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
This monoclonal antibody reacts with Mouse Tim-3.
Purification
Affinity chromatography on Protein G
Clone
25F-1D6
Isotype
IgG2a
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Discover our top product TIM 3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
PBS, 0.02 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TIM3
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Target
TIM3 (TIM 3)
(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
Alternative Name
TIMD3 / HAVCR2 (TIM 3 Products )
Synonyms
HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
Target Type
Virus
Background
This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.Synonyms: HAVCR-2, Hepatitis A virus cellular receptor 2, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3
Gene ID
171285
NCBI Accession
NP_599011
UniProt
Q8VIM0
Pathways
Regulation of Lipid Metabolism by PPARalpha , Cancer Immune Checkpoints
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