You are viewing an incomplete version of our website. Please click to reload the website as full version.

Tropomodulin 1 antibody (TMOD1) (AA 169-198)

Details for Product anti-TMOD1 Antibody No. ABIN955335, Supplier: Log in to see
Antigen
  • D9S57E
  • E-Tmod
  • ETMOD
  • si:ch211-288h2.6
  • Tmod
  • TMOD
  • TMOD1
  • tropomodulin-1
Epitope
AA 169-198, Middle Region
15
13
11
5
4
2
2
2
2
1
1
1
Reactivity
Human
59
9
9
4
2
1
1
1
1
1
Host
Rabbit
31
27
5
Clonality
Polyclonal
Conjugate
This Tropomodulin 1 antibody is un-conjugated
3
3
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
54
28
20
13
5
4
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human TMOD1
Isotype Ig
Specificity This antibody detects Tropomodulin-1 (TMOD1) (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name Tropomodulin-1 (TMOD1) (TMOD1 Antibody Abstract)
Background TMOD1 is a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.Synonyms: D9S57E, E-Tmod, Erythrocyte tropomodulin, TMOD
Gene ID 7111
NCBI Accession NP_001159588
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Tropomodulin 1 antibody (TMOD1) (AA 169-198) (ABIN955335) TMOD1 Antibody (Center) western blot analysis in A549 cell line lysates (35 µg/lane)....
Background publications Kong, Kedes: "Leucine 135 of tropomodulin-1 regulates its association with tropomyosin, its cellular localization, and the integrity of sarcomeres." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9589-99, 2006

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006

Vera, Lao, Hamelberg, Sung: "Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction." in: Archives of biochemistry and biophysics, Vol. 444, Issue 2, pp. 130-8, 2005

Pawlak, McGarvey, Nguyen, Tomaszewski, Puthiyaveettil, Malkowicz, Helfman: "Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder." in: International journal of cancer. Journal international du cancer, Vol. 110, Issue 3, pp. 368-73, 2004

Rho, Chun, Lee, Park, Lee: "The interaction between E-tropomodulin and thymosin beta-10 rescues tumor cells from thymosin beta-10 mediated apoptosis by restoring actin architecture." in: FEBS letters, Vol. 557, Issue 1-3, pp. 57-63, 2004