UBTF antibody (C-Term)

Catalog No. ABIN955436

Product Details anti-UBTF Antibody

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Binding Specificity: AA 630-660, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBTF antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects UBTF / UBF (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 630-660 amino acids from the C-terminal region of human UBTF

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Alternative Name: UBTF / UBF (UBTF Products)

Synonyms: NOR-90 antibody, UBF antibody, UBF-1 antibody, UBF1 antibody, A930005G04Rik antibody, Tcfubf antibody, wu:fj38c10 antibody, si:dz180g5.3 antibody, ubf antibody, Ubtf antibody, ubf1 antibody, xUBF antibody, xUBFbeta2 antibody, UBTF antibody, nor-90 antibody, ubf2 antibody, ubtf antibody, upstream binding transcription factor, RNA polymerase I antibody, upstream binding transcription factor, RNA polymerase I L homeolog antibody, upstream binding transcription factor, RNA polymerase I S homeolog antibody, UBTF antibody, Ubtf antibody, ubtf antibody, ubtf.L antibody, ubtf.S antibody

Background: Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).Synonyms: Autoantigen NOR-90, Nucleolar transcription factor 1, UBF-1, UBF1, Upstream-binding factor 1

Gene ID: 7343

NCBI Accession: NP_001070151