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Details for Product No. ABIN965629

AXL Receptor tyrosine Kinase (AXL) (AA 466-530) antibody

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Antigen
Synonyms Ark, Ufo, Tyro7, AI323647, UFO, JTK11
Epitope
»Alternatives AA 466-530
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), ELISA
Pubmed 3 references available
Catalog no. ABIN965629
Quantity 0.1 mL
Price
343.75 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.
Clone 1B3A2
Isotype IgG1
Purification Ascitic fluid
Alternative Name AXL
Background AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: UFO, JTK11
Gene ID 558
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Storage 4 °C
Product cited in: Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Budagian, Bulanova, Orinska et al.: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, 2005 (PubMed).

Collett, Sage, Kirton et al.: "Axl/phosphatidylinositol 3-kinase signaling inhibits mineral deposition by vascular smooth muscle cells." in: Circulation research, Vol. 100, Issue 4, pp. 502-9, 2007 (PubMed).

Alternatives for antigen "AXL Receptor tyrosine Kinase (AXL)", type "Antibodies"
Hosts (78), (26), (4), (1)
Reactivities (105), (48), (45), (34), (19), (17), (1)
Applications (77), (45), (37), (20), (16), (14), (9), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (18), (18), (9), (8), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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