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WD Repeat Domain 11 (WDR11) (N-Term) antibody

Details for Product No. ABIN965702, Supplier: Log in to see
Antigen
  • Brwd2
  • WDR11
  • PHIP
  • BRWD2
  • DR11
  • HH14
  • WDR15
  • 2900055P10Rik
  • AW489876
  • mKIAA1351
  • WD repeat domain 11
  • bromodomain and WD repeat domain containing 2
  • pleckstrin homology domain interacting protein
  • Wdr11
  • BRWD2
  • PHIP
  • WDR11
  • LOC100220549
Epitope
N-Term
14
10
7
3
2
Reactivity
Human
23
12
1
Host
Rabbit
23
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
20
15
15
2
1
1
1
1
1
Options
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human BRWD2 (Bromodomain and WD repeat-containing protein 2)
Alternative Name BRWD2 (WDR11 Antibody Abstract)
Background BRWD2 (Bromodomain and WD repeat-containing protein 2) contains 9 WD repeats. WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly, BRWD2 typically contains a GH dipeptide 11-24 residues. BRWD2 (Bromodomain and WD repeat-containing protein 2) is a single-pass membrane protein. A chromosomal aberration involving BRWD2 is found in a form of glioblastoma. Translocation t(10,19)(q26,q13.3) with ZNF320.
Synonyms: KIAA1351, WDR11 (WD repeat-containing protein 11), WDR15 (WD repeat-containing protein 15)
Restrictions For Research Use only
Background publications Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).

Nakajima, Okazaki, Yamakawa, Kikuno, Ohara, Nagase: "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 9, Issue 3, pp. 99-106, 2002 (PubMed).

Nagase, Kikuno, Ishikawa, Hirosawa, Ohara: "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 1, pp. 65-73, 2000 (PubMed).

Product cited in: Chernova, Hunyadi, Malaj, Pan, Crooks, Roe, Cowell: "A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells." in: Oncogene, Vol. 20, Issue 38, pp. 5378-92, 2001 (PubMed).