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CHEK1 antibody

CHEK1 Reactivity: Human WB, ELISA Monoclonal unconjugated
Catalog No. ABIN965882
  • Target See all CHEK1 Antibodies
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Reactivity
    • 212
    • 119
    • 68
    • 16
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    Please inquire
    Clonality
    • 210
    • 38
    Monoclonal
    Conjugate
    • 132
    • 13
    • 11
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    This CHEK1 antibody is un-conjugated
    Application
    • 170
    • 86
    • 53
    • 41
    • 40
    • 36
    • 35
    • 17
    • 16
    • 13
    • 10
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Ni-NTA purified recombinant protein CHK1 expressed in E. Coli strain M15.
    Purification
    Antibodies are purified by protein G affinity chromatography.
    Isotype
    IgG1
    Top Product
    Discover our top product CHEK1 Primary Antibody
  • Application Notes
    Western Blot: Dilution 1: 2,00- 1: 1,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Storage
    -20 °C
  • OConnell, Raleigh, Verkade, Nurse: "Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation." in: The EMBO journal, Vol. 16, Issue 3, pp. 545-54, (1997) (PubMed).

  • Target
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Alternative Name
    CHK1 (CHEK1 Products)
    Synonyms
    An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
    Background
    Active recombinant full length human CHK1 containing an Nterminal GST tag. This protein has an apparent molecular weight of ~82kDa. CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia.
    Pathways
    p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair
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