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Keratin 19 (KRT19) (C-Term) antibody

Details for Product No. ABIN965901, Supplier: Log in to see
Antigen
  • AI663979
  • CK19
  • ck19
  • EndoC
  • GK-19
  • k1cs
  • K1CS
  • k19
  • K19
  • Ka19
  • Krt-1.19
  • Krt1-19
  • krt9
  • krt15
  • KRT19
  • MGC76282
  • MGC83069
Epitope
C-Term
133
77
44
27
21
17
15
13
13
9
9
9
8
8
7
6
6
5
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
800
180
110
23
11
8
5
4
3
3
2
1
1
1
1
1
Host
Rabbit
593
209
18
5
2
Clonality
Polyclonal
Conjugate
Un-conjugated
44
28
26
18
14
14
14
14
14
14
13
13
12
12
12
12
12
7
6
6
2
2
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
549
393
270
264
241
240
199
166
126
12
10
9
4
3
2
2
1
1
1
1
1
1
1
Supplier
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Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human CK19.< br/>Immunogen was affinity purified.
Isotype IgG
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Keratin, type I cytoskeletal 19 (KRT19) detection. Tested with WB, IHC-P, ICC in Human.
Alternative Name Keratin, type I cytoskeletal 19 (KRT19 Antibody Abstract)
Background Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene. The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Sodium azide, Thimerosal (Merthiolate)
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
Product cited in: Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, 2006 (PubMed).