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EHV-1 GP2 (C-Term) antibody

Details for Product No. ABIN966048, Supplier: Log in to see
Antigen
Epitope
C-Term
1
Reactivity
Equine Herpes Virus 1 (ESV-1)
1
Host
Rabbit
1
Clonality
Polyclonal
Application
Immunohistochemistry (IHC)
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Wild-type equine herpesvirus 1 (EHV-1) glycoprotein, gp2
Background Wild-type equine herpesvirus 1 (EHV-1) strains express a large (250-kDa) glycoprotein, gp2, that is encoded by EUs4 (gene 71) located within the unique short region of the genome. The expression of full-length gp2 restore full respiratory virulence to the attenuated strain.
Restrictions For Research Use only
Product cited in: Smith, Kahan, Rorex, von Einem, Osterrieder, OCallaghan: "Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice." in: Journal of virology, Vol. 79, Issue 8, pp. 5105-15, 2005 (PubMed).

von Einem, Wellington, Whalley, Osterrieder, OCallaghan, Osterrieder: "The truncated form of glycoprotein gp2 of equine herpesvirus 1 (EHV-1) vaccine strain KyA is not functionally equivalent to full-length gp2 encoded by EHV-1 wild-type strain RacL11." in: Journal of virology, Vol. 78, Issue 6, pp. 3003-13, 2004 (PubMed).

Learmonth, Love, Gilkerson, Wellington, Whalley: "Inoculation with DNA encoding the glycoprotein gp2 reduces severity of equine herpesvirus 1 infection in a mouse respiratory model." in: Archives of virology, Vol. 148, Issue 9, pp. 1805-13, 2003 (PubMed).