FANCG antibody (C-Term)

Catalog No. ABIN966129

Cited in 3+ publications. The Rabbit Polyclonal anti-FANCG antibody (ABIN966129) specifically detects FANCG in IHC. The antibody is reactive with Human samples.

Quick Overview for FANCG antibody (C-Term) (ABIN966129)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-FANCG Antibody

Binding Specificity: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human FANCG (Fanconi anemia group G protein)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-FANCG antibody (ABIN966129)

Meetei, Levitus, Xue, Medhurst, Zwaan, Ling, Rooimans, Bier, Hoatlin, Pals, de Winter, Wang, Joenje: "X-linked inheritance of Fanconi anemia complementation group B." in: Nature genetics, Vol. 36, Issue 11, pp. 1219-24, (2004) (PubMed).

Demuth, Wlodarski, Tipping, Morgan, de Winter, Thiel, Gräsl, Schindler, DAndrea, Altay, Kayserili, Zatterale, Kunze, Ebell, Mathew, Joenje, Sperling, Digweed: "Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9." in: European journal of human genetics : EJHG, Vol. 8, Issue 11, pp. 861-8, (2000) (PubMed).

Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: "Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex." in: Molecular and cellular biology, Vol. 19, Issue 7, pp. 4866-73, (1999) (PubMed).

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCG may be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCG is a andidate tumor suppressor gene. FANCG belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. The major form is nuclear. The minor form is cytoplasmic. Highly expressed in testis and thymus. Found in lymphoblasts. Defects in FANCG are a cause of Fanconi anemia (FA)
Synonym: XRCC9 (DNA repair protein XRCC9)

Pathways: DNA Damage Repair