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Growth Differentiation Factor 15 (GDF15) (C-Term) antibody

Details for Product No. ABIN966196, Supplier: Log in to see
Antigen
  • GDF15
  • GDF-15
  • MIC-1
  • MIC1
  • NAG-1
  • PDF
  • PLAB
  • PTGFB
  • SBF
Epitope
C-Term
79
51
17
16
15
13
11
7
6
5
5
4
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
257
79
38
7
7
2
2
Host
Rabbit
228
27
19
5
Clonality
Polyclonal
Conjugate
Un-conjugated
34
28
13
5
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
236
203
79
25
23
12
11
6
5
4
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse GDF-15 (Growth Differentiation factor 15)
Alternative Name GDF-15 (GDF15 Antibody Abstract)
Background GDF-15 (Growth Differentiation factor 15) is a transforming growth factor beta superfamily member induced following liver injury. GDF-15 is a homodimer and disulfide-linked by similarity. GDF-15 is secreted and highly expressed in liver. GDF-15 belongs to the TGF-beta family.
Synonyms: Macrophage inhibiting cytokine-1(MIC-1)
Pathways
Restrictions For Research Use only
Product cited in: Cekanova, Lee, Donnell et al.: "Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice." in: Cancer prevention research (Philadelphia, Pa.), Vol. 2, Issue 5, pp. 450-8, 2009 (PubMed).

Iguchi, Chrysovergis, Lee et al.: "A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2." in: Cancer letters, Vol. 282, Issue 2, pp. 152-8, 2009 (PubMed).

Ding, Mracek, Gonzalez-Muniesa et al.: "Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes." in: Endocrinology, Vol. 150, Issue 4, pp. 1688-96, 2009 (PubMed).

Zimmers, Jin, Gutierrez et al.: "Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis." in: Journal of cancer research and clinical oncology, Vol. 134, Issue 7, pp. 753-9, 2008 (PubMed).

Noorali, Kurita, Woolcock et al.: "Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse." in: Differentiation; research in biological diversity, Vol. 75, Issue 4, pp. 325-36, 2007 (PubMed).

Oxburgh, Chu, Michael et al.: "TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population." in: Development (Cambridge, England), Vol. 131, Issue 18, pp. 4593-605, 2004 (PubMed).

Zambrowicz, Abuin, Ramirez-Solis et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, 2003 (PubMed).