ITK antibody

Catalog No. ABIN966423

Cited in 1 publication. The Mouse Monoclonal anti-ITK antibody (Clone 5G6) (ABIN966423) specifically detects ITK in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for ITK antibody (ABIN966423)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 5G6

Product Details anti-ITK Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ITK expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-ITK antibody (ABIN966423)

Bradley, Griffin, Livingston: "Relationship of oligomerization to enzymatic and DNA-binding properties of the SV40 large T antigen." in: Cell, Vol. 28, Issue 1, pp. 125-34, (1982) (PubMed).

Target Details for ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Alternative Name: ITK

Background: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Synonyms: EMT, LYK, PSCTK2, MGC126257, MGC126258

Molecular Weight: 72kDa

Gene ID: 3702

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway