anti-Jak2 antibody (Janus Kinase 2)

Details for Product anti-JAK2 Antibody No. ABIN966432
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Antigen
Synonyms JAK2bCA, jak2, JTK10, THCYT3, AI504024, C81284, Fd17, JAK-2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(245), (166), (164), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(246), (10), (5)
Clonality
Polyclonal
Conjugate
This Jak2 antibody is un-conjugated
(10), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (IHC)
(175), (117), (115), (35), (30), (23), (14), (10), (9), (6), (3), (3), (1)
Pubmed 2 references available
Quantity 100 μg
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
Specificity JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name JAK2 (JAK2 Antibody Abstract)
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Feener, Rosario, Dunn et al.: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, 2004 (PubMed).

Argetsinger, Kouadio, Steen et al.: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, 2004 (PubMed).

Validation Images
Catalog No. ABIN966432
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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