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JAK2 antibody

JAK2 Reactivity: Human, Rat, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966432
  • Target See all JAK2 Antibodies
    JAK2 (Janus Kinase 2 (JAK2))
    Reactivity
    • 173
    • 101
    • 97
    • 18
    • 18
    • 3
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 175
    • 6
    • 2
    Rabbit
    Clonality
    • 159
    • 24
    Polyclonal
    Conjugate
    • 93
    • 15
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This JAK2 antibody is un-conjugated
    Application
    • 131
    • 81
    • 62
    • 57
    • 29
    • 27
    • 25
    • 22
    • 17
    • 13
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
    Top Product
    Discover our top product JAK2 Primary Antibody
  • Application Notes
    IHC: 1:50-1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Feener, Rosario, Dunn, Stancheva, Myers: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, (2004) (PubMed).

    Argetsinger, Kouadio, Steen, Stensballe, Jensen, Carter-Su: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, (2004) (PubMed).

  • Target
    JAK2 (Janus Kinase 2 (JAK2))
    Alternative Name
    JAK2 (JAK2 Products)
    Synonyms
    JAK2bCA antibody, jak2 antibody, JTK10 antibody, THCYT3 antibody, AI504024 antibody, C81284 antibody, Fd17 antibody, JAK-2 antibody, Janus kinase 2b antibody, Janus kinase 2 antibody, jak2b antibody, JAK2 antibody, Jak2 antibody
    Pathways
    JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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