Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

Details for Product No. ABIN966497
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Antigen
Synonyms
KDM1, AOF2, KDM1A, DKFZp459N2450, aof2, kdm1, lsd1, xLSD1, BHC110, LSD1, 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601, RGD1562975, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, A ... show more
KDM1, AOF2, KDM1A, DKFZp459N2450, aof2, kdm1, lsd1, xLSD1, BHC110, LSD1, 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601, RGD1562975, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE, ATLSD1, ATSWP1, F23N19.21, F23N19_21, LSD1-like 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE, SWP1 show less
Reactivity
Human
(165), (75), (66), (13), (9), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host
(132), (37), (1)
Clonality
Monoclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
(143), (48), (44), (36), (22), (20), (10), (6), (5), (4), (4), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Isotype IgG1
Specificity Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)
Purification Crude Asites are purified by protein A affinity chromatography.
Alternative Name LSD1/AOF2 (KDM1A Antibody Abstract)
Background The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Gene ID 23028
Application Notes Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Storage -20 °C
Product cited in: Metzger, Wissmann, Yin et al.: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).

Validation Images
Catalog No. ABIN966497
412.50 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
412.50 $

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