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Details for Product No. ABIN966497

Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

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Antigen
Synonyms
AOF2, BHC110, KDM1, LSD1, 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601, RGD1562975, aof2, kdm1, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, ARABIDOPSIS LYSINE-SPECIFIC HISTONE  ... show more
Reactivity
»Alternatives Human
Host
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Pubmed 1 reference available
Catalog no. ABIN966497
Quantity 0.1 mg
Price
398.75 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Isotype IgG1
Specificity Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)
Purification Crude Asites are purified by protein A affinity chromatography.
Alternative Name LSD1/AOF2
Background The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Gene ID 23028
Application Notes Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Product cited in: Metzger, Wissmann, Yin et al.: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).

Alternatives for antigen "Lysine (K)-Specific Demethylase 1A (KDM1A)", type "Antibodies"
Hosts (105), (31), (1)
Reactivities (134), (75), (59), (38), (29), (28), (24), (18), (4), (2), (2), (1), (1), (1), (1)
Applications (114), (54), (43), (21), (20), (12), (6), (5), (3), (3), (3), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (15), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
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