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MAP2K3 antibody (Mitogen-Activated Protein Kinase Kinase 3)

Details for Product anti-MAP2K3 Antibody No. ABIN966579, Supplier: Login to see
Antigen
  • Mkk3
  • MAPKK3
  • MEK3
  • MKK3
  • PRKMK3
  • SAPKK-2
  • SAPKK2
  • AW212142
  • Prkmk3
  • mMKK3b
  • map2k3
  • zMKK3
Alternatives
anti-Human MAP2K3 antibody for Western Blotting
Reactivity
Human, Rat (Rattus)
280
108
108
28
17
3
2
1
1
1
Host
Rabbit
201
82
Clonality
Polyclonal
Conjugate
This MAP2K3 antibody is un-conjugated
7
7
6
3
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC)
237
87
81
81
47
23
15
8
3
2
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human MKK3 around the phosphorylation site of serine189 (V-D-SP-V-A).
Specificity MKK3 (Ab-189) antibody detects endogenous levels of total MKK3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name MKK3 (MAP2K3 Antibody Abstract)
Pathways MAPK Signaling, TLR Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Wang, Chen, Liao et al.: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, 2002 (PubMed).

Background publications Raingeaud, Whitmarsh, Barrett et al.: "MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1247-55, 1996 (PubMed).