Phospholipase C gamma 2 antibody (PLCG2)

Details for Product anti-PLCG2 Antibody No. ABIN966863, Supplier: Log in to see
Antigen
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
Alternatives
anti-Human Phospholipase C gamma 2 antibody for Immunofluorescence (fixed cells)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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70
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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Options
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human PLC2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).
Specificity PLC2 (Ab-753) antibody detects endogenous levels of total PLC2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name PLCgamma2 (PLCG2 Antibody Abstract)
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Kim, Sekiya, Poulin, Bae, Rhee: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, 2004 (PubMed).

Suzuki-Inoue, Wilde, Andrews, Auger, Siraganian, Sekiya, Rhee, Watson: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, 2004 (PubMed).