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Reticulon 3 antibody

RTN3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E11 unconjugated
Catalog No. ABIN966979
  • Target See all Reticulon 3 (RTN3) Antibodies
    Reticulon 3 (RTN3)
    Reactivity
    • 17
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 12
    • 5
    Mouse
    Clonality
    • 14
    • 3
    Monoclonal
    Conjugate
    • 17
    This Reticulon 3 antibody is un-conjugated
    Application
    • 13
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of RTN3 expressed in E. Coli.
    Clone
    1E11
    Isotype
    IgG2a
    Top Product
    Discover our top product RTN3 Primary Antibody
  • Application Notes
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." in: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

    Brain, Wilson, Johnson, Sanderson, Bestari, Hanson, Sibley, Solomon: "Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms." in: Environmental pollution (Barking, Essex : 1987), Vol. 138, Issue 3, pp. 425-42, (2005) (PubMed).

    Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." in: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

    Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

  • Target
    Reticulon 3 (RTN3)
    Alternative Name
    RTN3 (RTN3 Products)
    Synonyms
    ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody
    Background
    RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
    Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1
    Molecular Weight
    113kDa
    Gene ID
    10313
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