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Microtubule-Associated Protein tau (MAPT) antibody

Details for Product No. ABIN967158
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Antigen
Synonyms tau, xtp, MAPT, AI426939, AI551861, AW457082, CK1epsilon, CKIe, KC1epsilon, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU, AI413597, AW045860, Mtapt, Tau, PHF-tau, RNPTAU, pTau
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(858), (451), (424), (43), (8), (6), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(797), (87), (10), (8), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (4), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (IHC)
(792), (343), (238), (91), (76), (60), (31), (30), (16), (13), (13), (13), (9), (3), (1), (1), (1)
Pubmed 4 references available
Quantity 100 µg
Options
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Catalog No. ABIN967158
385.00 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of serine 404 (D-T-SP-P-R).
Specificity Tau (Ab-404) antibody detects endogenous levels of total Tau protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Tau
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Andreadis, Brown, Kosik: "Structure and novel exons of the human tau gene." in: Biochemistry, Vol. 31, Issue 43, pp. 10626-33, 1992 (PubMed).

Giasson, Sampathu, Wilson et al.: "The environmental toxin arsenite induces tau hyperphosphorylation." in: Biochemistry, Vol. 41, Issue 51, pp. 15376-87, 2002 (PubMed).

Gustin, Ozes, Akca et al.: "Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1615-20, 2004 (PubMed).

Li, Yin, Kuret: "Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 15938-45, 2004 (PubMed).

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