TIMP1 antibody (C-Term)

Catalog No. ABIN967182

Product Details anti-TIMP1 Antibody

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Binding Specificity: AA 189-207, C-Term

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This TIMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human TIMP1 (189-207 aa), identical to the related mouse and rat sequence.

Application Details

Application Notes: WB: The detection limit for TIMP1 is approximately 2.5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

Target Details for TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Alternative Name: TIMP1 (TIMP1 Products)

Synonyms: TIMP-1 antibody, TIMP1 antibody, DKFZp468A0912 antibody, CLGI antibody, EPA antibody, EPO antibody, HCI antibody, TIMP antibody, Timp antibody, Clgi antibody, TIMP metallopeptidase inhibitor 1 antibody, tissue inhibitor of metalloproteinase 1 antibody, TIMP1 antibody, Timp1 antibody

Background: TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).