TNFAIP1 antibody (N-Term)

Catalog No. ABIN967193

Product Details anti-TNFAIP1 Antibody

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 ( TNFAIP1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human TNFalphaIP1, identical to the related rat and mouse sequence.< br/>Immunogen was affinity purified.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

References for anti-TNFAIP1 antibody (ABIN967193)

He, Tan, Downey, So: "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 21, pp. 11979-84, (2001) (PubMed).

Wolf, Marks, Sarma, Byers, Katz, Shows, Dixit: "Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene." in: The Journal of biological chemistry, Vol. 267, Issue 2, pp. 1317-26, (1992) (PubMed).

Target Details for TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Alternative Name: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2(hBACURD2) (TNFAIP1 Products)

Synonyms: zgc:55302 antibody, wu:fi06b02 antibody, TNFAIP1 antibody, B12 antibody, B61 antibody, BTBD34 antibody, EDP1 antibody, hBACURD2 antibody, Edp-1 antibody, Edp1 antibody, Tnfip1 antibody, tumor necrosis factor, alpha-induced protein 1 (endothelial) antibody, TNF alpha induced protein 1 antibody, TNF alpha induced protein 1 L homeolog antibody, tnfaip1 antibody, TNFAIP1 antibody, Tnfaip1 antibody, tnfaip1.L antibody

Background: Tumor necrosis factor, alpha-induced protein 1 (endothelial), also known as TNFAIP1, is a human gene. The gene, present in single copy, was located in the 17q22-q23 region. ssThis gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. The protein is involved in the primary response of the endothelium to TNF.