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WIF1 antibody (WNT Inhibitory Factor 1)

Details for Product anti-WIF1 Antibody No. ABIN967258, Supplier: Log in to see
Antigen
  • AW107799
  • GB10372
  • shf
  • WIF-1
  • wif-1
  • WIF1
  • zgc:110507
Alternatives
anti-Human WIF1 antibody for ELISA
Reactivity
Human
107
20
20
Host
Mouse
93
17
3
Clonality (Clone)
Monoclonal ()
Conjugate
This WIF1 antibody is un-conjugated
7
7
6
6
6
5
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
91
55
45
17
14
11
6
3
1
1
1
Supplier
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Immunogen Purified recombinant fragment of human WIF1 expressed in E. Coli.
Clone 1G5
Isotype IgG1
Purification Ascitic fluid
Alternative Name WIF1 (WIF1 Antibody Abstract)
Background The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Synonyms: WIF-1, WIF
Molecular Weight 42kDa
Gene ID 11197
Research Area Stem Cells, Wnt Signaling
Pathways WNT Signaling
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Yu, Chen, Yang, Qiu, Fan, Xu, Shao: "Current evidence on the relationship between polymorphisms in the COX-2 gene and breast cancer risk: a meta-analysis." in: Breast cancer research and treatment, Vol. 122, Issue 1, pp. 251-7, 2010 (PubMed).

Product cited in: Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, 2009 (PubMed).

Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, 2009 (PubMed).