Jun Proto-Oncogene (JUN) (AA 26-175) antibody

Details for Product No. ABIN967903
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Antigen
Synonyms
BSK, BSK/DJNK, Bsk, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, DJNK/bsk, Dmel\\CG5680, JNK, JNK/SAPK, Jnk, Junk, SAPKa, c-Jun, dJNK, jnk, Jun, AP-1, JUN, B230310J22Rik, p39, Junc, c-jun, AP1, fj36h07, wu: ... show more
BSK, BSK/DJNK, Bsk, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, DJNK/bsk, Dmel\\CG5680, JNK, JNK/SAPK, Jnk, Junk, SAPKa, c-Jun, dJNK, jnk, Jun, AP-1, JUN, B230310J22Rik, p39, Junc, c-jun, AP1, fj36h07, wu:fj36h07, zgc:65863, CG2275, D-Jun, D-jun, D-jun/Jra, DJUN, DJun, Djun, Dmel\\CG2275, JRA, V, cJun, d-JRA, d-Jun, d-jun, dAP-1, dJRA, dJUN, dJra, dJun, djun, dm-Jun, jra, jun, l(2)46Ef, l(2)IA109, l(2R)IA109 show less
Epitope
AA 26-175
(70), (59), (54), (45), (37), (34), (28), (20), (15), (13), (12), (9), (8), (7), (6), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(604), (414), (373), (154), (152), (150), (139), (10), (7), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Host
Mouse
(568), (55), (2), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(16), (16), (16), (12), (12), (12), (12), (12), (12), (12), (12), (4), (4), (4)
Application
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
(465), (232), (168), (119), (113), (62), (52), (43), (19), (8), (8), (8), (2), (1), (1)
Pubmed 5 references available
Quantity 50 µg
Options
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Catalog No. ABIN967903
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Immunogen Mouse c-Jun
Clone 3
Isotype IgG2a
Cross-Reactivity Human, Chicken, Dog (Canine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name Jun
Background The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the SV40 virus and the human metallothionein IIA gene. AP-1 is composed of protein products of two different gene families: jun and fos. The AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins. The transcriptional activity of Jun is enhanced by phosphorylation in its activation domain at Ser63 and Ser73. Phosphorylation at both sites is necessary for stimulating the activating function of Jun. Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity. This antibody is routinely tested by western blot analysis.
Molecular Weight 39 kDa
Comment

Related Products: ABIN968536, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Jun Proto-Oncogene (JUN) (AA 26-175) antibody Western blot analysis of Jun on human endothelial cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-Jun antibody.
anti-Jun Proto-Oncogene (JUN) (AA 26-175) antibody (2) Immunohistochemical staining of Rabbit Muscle tissue section. SDS-treated formalin-fixed paraffin-embedded section.
anti-Jun Proto-Oncogene (JUN) (AA 26-175) antibody (3) Immunohistochemical staining of rat brain. Formalin-fixed paraffin-embedded section with citrate buffer pretreatment. 40X.
Product cited in: Lamph, Wamsley, Sassone-Corsi et al.: "Induction of proto-oncogene JUN/AP-1 by serum and TPA." in: Nature, Vol. 334, Issue 6183, pp. 629-31, 1988 (PubMed).

Taupin, Wu, Jeon et al.: "The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation." in: The Journal of clinical investigation, Vol. 103, Issue 9, pp. R31-8, 1999 (PubMed).

Chang, Nakajima, Illenye et al.: "Caspase-dependent apoptosis by ectopic expression of E2F-4." in: Oncogene, Vol. 19, Issue 41, pp. 4713-20, 2000 (PubMed).

He, Stepulak, Holmström et al.: "The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase." in: The Journal of biological chemistry, Vol. 277, Issue 13, pp. 10767-74, 2002 (PubMed).

Doray, Ghosh, Griffith et al.: "Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network." in: Science (New York, N.Y.), Vol. 297, Issue 5587, pp. 1700-3, 2002 (PubMed).

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