CHD3 antibody
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- Target See all CHD3 Antibodies
- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CHD3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CHD3 expressed in E. coli.
- Clone
- 2G4
- Isotype
- IgG1
- Top Product
- Discover our top product CHD3 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).
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UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).
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- Target
- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
- Alternative Name
- CHD3 (CHD3 Products)
- Synonyms
- CG9594 antibody, CHD-3 antibody, CHD3 antibody, DmCHD3 antibody, Dmel\\CG9594 antibody, chd3 antibody, dCHD3 antibody, LOC568230 antibody, zfh antibody, mi-2a antibody, mi2-alpha antibody, Mi-2a antibody, Mi2-ALPHA antibody, ZFH antibody, 2600010P09Rik antibody, AF020312 antibody, Chd7 antibody, Prp7 antibody, Prp9-1 antibody, CG9594 gene product from transcript CG9594-RA antibody, chromodomain helicase DNA binding protein 3 antibody, chromodomain-helicase-DNA-binding protein 3 antibody, Chd3 antibody, CHD3 antibody, chd3 antibody, LOC100480350 antibody
- Background
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Description: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Aliases: ZFH, Mi-2a, Mi2-ALPHA, CHD3
- Molecular Weight
- 226 kDa
- Gene ID
- 1107
- HGNC
- 1107
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