EPH Receptor B3 antibody (EPHB3) (AA 39-212)

Details for Product anti-EPHB3 Antibody No. ABIN969106, Supplier: Log in to see
Antigen
  • tck
  • MGC83457
  • EPHB3
  • ETK2
  • HEK2
  • TYRO6
  • AW456895
  • Cek10
  • Etk2
  • MDK5
  • Sek4
  • Tyro6
  • CEK10
  • EK10
  • ek3
  • ephb3
  • fc62d03
  • rtk3
  • wu:fc62d03
  • zek3
  • EPH receptor B3
  • Eph receptor B3
  • eph receptor B3a
  • Eph receptor tyrosine kinase
  • EPHB3
  • ephb3
  • Ephb3
  • ephb3a
Alternatives
anti-Mouse (Murine) EPH Receptor B3 antibody for ELISA
Epitope
AA 39-212
22
14
11
8
6
6
6
4
4
4
4
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
126
47
33
7
7
3
2
2
2
2
2
2
1
1
Host
Mouse
78
56
2
2
Clonality (Clone)
Monoclonal ()
Conjugate
This EPH Receptor B3 antibody is un-conjugated
6
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
90
53
38
29
29
13
3
3
2
2
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of EphB3 (aa39-212) expressed in E. Coli.
Clone 4A122D1
Isotype IgG2a
Purification Ascites
Alternative Name EphB3 (EPHB3 Antibody Abstract)
Background EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Gene ID 2049
HGNC 2049
Pathways RTK Signaling
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunohistochemistry (IHC) image for anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody (ABIN969106) Figure 1: Immunohistochemical analysis of paraffin-embedded human lung squamous cell ...
Immunohistochemistry (IHC) image for anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody (ABIN969106) Figure 2: Immunohistochemical analysis of paraffin-embedded human Adrenal tissues usi...
Western Blotting (WB) image for anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody (ABIN969106) Figure 3: Western blot analysis using EphB3 mouse mAb against truncated EphB3-His rec...
Product cited in: Trivier, Ganesan: "RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 23037-43, 2002 (PubMed).

Bergemann, Zhang, Chiang, Brambilla, Klein, Flanagan: "Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube." in: Oncogene, Vol. 16, Issue 4, pp. 471-80, 1998 (PubMed).

Hock, Böhme, Karn, Yamamoto, Kaibuchi, Holtrich, Holland, Pawson, Rübsamen-Waigmann, Strebhardt: "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 17, pp. 9779-84, 1998 (PubMed).

Background publications Zhou: "The Eph family receptors and ligands." in: Pharmacology & therapeutics, Vol. 77, Issue 3, pp. 151-81, 1998 (PubMed).

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