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CD86 antibody (C-Term)

CD86 Reactivity: Human, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN970351
  • Target See all CD86 Antibodies
    CD86
    Binding Specificity
    • 16
    • 9
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 132
    • 107
    • 50
    • 20
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    Human, Pig
    Host
    • 77
    • 63
    • 59
    Rabbit
    Clonality
    • 137
    • 59
    • 1
    Polyclonal
    Conjugate
    • 79
    • 21
    • 16
    • 13
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD86 antibody is un-conjugated
    Application
    • 136
    • 90
    • 38
    • 35
    • 33
    • 30
    • 23
    • 20
    • 16
    • 16
    • 14
    • 13
    • 13
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT
    Predicted Reactivity
    Human: 100%, Pig: 92%
    Characteristics
    This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product CD86 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 217 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CD86
    Alternative Name
    CD86 (CD86 Products)
    Synonyms
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    Background
    This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
    Alias Symbols: B7-2, B70, CD28LG2, LAB72, MGC34413, B7.2
    Protein Interaction Partner: UBC, CTLA4, ECE2, PARP1, MARCH1, MARCH8, CD86, CD28, CD80,
    Protein Size: 217
    Molecular Weight
    23 kDa
    Gene ID
    942
    NCBI Accession
    NM_175862, NP_787058
    UniProt
    E9PC27
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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