DTNA antibody (C-Term)

Catalog No. ABIN970563

Product Details anti-DTNA Antibody

Target: DTNA (Dystrobrevin alpha (DTNA))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GATTSTMRGD MVTEDADPYV QPEDENYEND SVRQLENELQ MEEYLKQKLQ

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against DTNA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 452 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: DTNA (DTNA Products)

Synonyms: adtn antibody, atnb antibody, MGC146484 antibody, 2210407P21Rik antibody, A0 antibody, Dtn antibody, a-DB-1 antibody, adbn antibody, D18S892E antibody, DRP3 antibody, DTN antibody, DTN-A antibody, LVNC1 antibody, Dtna-ps1 antibody, RGD1561985 antibody, dystrobrevin alpha antibody, dystrobrevin, alpha antibody, DTNA antibody, dtna antibody, LOC100195747 antibody, Dtna antibody

Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: D18S892E, DRP3, DTN, FLJ96209, LVNC1
Protein Interaction Partner: SNTA1, ADRA1D, TJP1, ACTB, MLC1, NUP62, SEC23A, SEC24C, PSEN1, MYO1E, GFI1B, MARK2, SYNC, SNTG2, SNTG1, KCNJ12, SYNM, DTNBP1, SNTB2, SNTB1, DMD, DRP2, UTRN, ACTA1,
Protein Size: 452

Molecular Weight: 49 kDa

Gene ID: 1837

NCBI Accession: NM_001198942, NP_001185871

UniProt: B4DIR0