RNGTT antibody (N-Term)

Catalog No. ABIN971586

Product Details anti-RNGTT Antibody

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNGTT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DLTNTSRFYD RNDIEKEGIK YIKLQCKGHG ECPTTENTET FIRLCERFNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Rngtt. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rngtt

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 597 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNGTT

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Alternative Name: Rngtt (RNGTT Products)

Synonyms: xcap1b antibody, MGC75787 antibody, CAP1A antibody, HCE antibody, HCE1 antibody, hCAP antibody, AU020997 antibody, zgc:76886 antibody, RNA guanylyltransferase and 5'-phosphatase antibody, mRNA-capping enzyme antibody, rngtt.S antibody, rngtt antibody, RNGTT antibody, LOC100439097 antibody, Rngtt antibody

Background: Rngtt is a bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. It catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
Alias Symbols: AU020997
Protein Size: 597

Molecular Weight: 69 kDa

Gene ID: 24018

NCBI Accession: NM_011884, NP_036014

UniProt: O55236