Aromatase antibody
Quick Overview for Aromatase antibody (ABIN126953)
Target
See all Aromatase (CYP19A1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody recognizes Aromatase p450AROM.
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Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat, Rabbit, Bovine, Sheep, Porcine, Equine (Horse) and Chicken.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic peptide surronding amino acid 385 of Human Aromatase Genename: CYP19A1
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anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 234-503) antibody
CYP19A1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 41-140) antibodyCYP19A1 Reactivity: Human, Rat, Mouse, Cow WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 1-180) antibodyCYP19A1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 453-485), (C-Term) antibodyCYP19A1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14708 unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Monoclonal 1H1 unconjugated Recombinant Antibody
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 Reactivity: Human WB, ICC, FACS Host: Rabbit Monoclonal 23GB5770 unconjugated Recombinant Antibody
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 1-503) antibodyCYP19A1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (Internal Region) antibodyVerified CYP19A1 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 51-150) antibodyCYP19A1 Reactivity: Human, Mouse, Sheep WB, ELISA, IHC (p) Host: Mouse Polyclonal unconjugated
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Application Notes
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Immunohistochemistry (10-20 μg/mL). Western blotting (0.5-4 μg/mL): A 55 kDa band can be detected, corresponding to theexpected molecular weight of Aromatase, an additional 35 kDa band (believed to be thecleavage product of Aromatase) can also be detected in Jurkat cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS containing 30 % Glycerol, 0.5 % BSA, 5 mM EDTA and 0.01 % Thimerosal as preservative
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody at -20 °C or aliquot and freeze at -70 °C for long term storage. Should this product contain a precipitate we recommend microcentrifugation before use.
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- Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
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Alternative Name
- Aromatase
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Background
- Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, oestrogen biosynthesis, fertility and carcinogenesis. It is highly conserved amongst mammals, and is highly expressed in placental tissue. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.Synonyms: ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P450AROM
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Gene ID
- 1588, 9606
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UniProt
- P11511
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
Target
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