Browse our BID Proteins (BID)

Full name:
BH3 Interacting Domain Death Agonist Proteins (BID)
On are 47 BH3 Interacting Domain Death Agonist (BID) Proteins from 13 different suppliers available. Additionally we are shipping BID Antibodies (419) and BID Kits (60) and many more products for this protein. A total of 582 BID products are currently listed.
2700049M22Rik, AI875481, AU022477, bid, DKFZp469E066, FP497, si:ch211-238n5.6, xbid
list all proteins Gene Name GeneID UniProt
BID 637 P55957
BID 12122 P70444
BID 64625 Q9JLT6

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BID Proteins (BID) by Origin

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Top referenced BID Proteins

  1. Human BID Protein expressed in Escherichia coli (E. coli) - ABIN668038 : Li, Zhu, Xu, Yuan: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. in Cell 1998 (PubMed)
    Show all 3 references for 668038

  2. Human BID Protein expressed in Escherichia coli (E. coli) - ABIN2002908 : Yin: Bid, a BH3-only multi-functional molecule, is at the cross road of life and death. in Gene 2006 (PubMed)
    Show all 2 references for 2002908

  3. Mouse (Murine) BID Protein expressed in Escherichia coli (E. coli) - ABIN2007708 : Culmsee, Plesnila: Targeting Bid to prevent programmed cell death in neurons. in Biochemical Society transactions 2006 (PubMed)
    Show all 2 references for 2007708

More Proteins for BID Interaction Partners

Zebrafish BH3 Interacting Domain Death Agonist (BID) interaction partners

  1. Stage-specific expression of TNFalpha (show TNF Proteins) regulates bad/bid-mediated apoptosis and RIP1 (show RALBP1 Proteins)/ROS (show ROS1 Proteins)-mediated secondary necrosis in Birnavirus-infected fish cells.

Xenopus laevis BH3 Interacting Domain Death Agonist (BID) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3 (show CASP3 Proteins)-dependent Proteolysis of JNK1 (show MAPK8 Proteins)-2 and Bid.

  2. tail regression at metamorphosis implicates an apoptotic pathway inducible by T(3) hormone in an organ autonomous manner and involving the cell death executioners BID and Caspases-2 and -8

  3. Here, we identified and characterized the Xenopus homologs of caspase-10 (show CASP10 Proteins) (xCaspase-10beta), a novel initiator caspase (show CASP3 Proteins), and Bid (xBid), a BH3-only (show BBC3 Proteins) molecule of the Bcl-2 (show BCL2 Proteins) family involved in both the extrinsic and intrinsic pathways.

  4. diubiquitylation is a specific feature of xBid.

Human BH3 Interacting Domain Death Agonist (BID) interaction partners

  1. an oligomeric arrangement of Bid, Bax (show BAX Proteins), and possibly other members of the Bcl-2 (show BCL2 Proteins) family of proteins that form a self-propagating network that permeabilizes the outer-mitochondrial membrane.

  2. Combined therapy with Seliciclib((R)) and Belinostat((R)) results in eradication of non-small cell lung cancer via apoptosis induction and BID activation.

  3. Results from genome-wide DNA methylation, functional network analysis and pyrosequencing, show selective CpG sites (NOS1AP, BID, and GABRB1) differentially methylated in smokers and chronic obstructive pulmonary disease patients compared to nonsmokers.

  4. The adenovirus-mediated truncated Bid overexpression induced by the Cre/LoxP system can effectively eliminate CD133+ ovarian cancer stem cells, representing a novel therapeutic strategy for the treatment of ovarian cancer.

  5. MiR (show MLXIP Proteins)-20a-directed regulation of BID in colorectal cancer.

  6. the results establish that cleavage by caspase 8 (show CASP8 Proteins) and the subsequent association with the outer mitochondrial membrane are two critical events that activate Bid during death receptor-mediated apoptosis.

  7. The results indicate that BID-independent pathways are responsible for FAS (show FAS Proteins)-dependent human islet cell death in Type 1 diabetes.

  8. The BID-MTCH2 (show MTCH2 Proteins) axis regulates the differentiation/apoptosis of stem cells and mitochondrial metabolism. (Review)

  9. Data suggest, in models of spatial propagation of mitochondrial permeabilization during apoptosis, there appears to be requirement for cooperative signaling involving truncated-BID and ROS (show ROS1 Proteins) (reactive oxygen species) for efficient/ robust propagation.

  10. this study emphasizes that the coordinated action of hGzmB-activated p53 and GzmB-cleaved Bid is important for GzmB-induced cell death and for cytotoxic lymphocyte/Natural Killer Cell-mediated killing of target cells.

Mouse (Murine) BH3 Interacting Domain Death Agonist (BID) interaction partners

  1. toxic reactive oxygen species levels in Mll5(-/-) mice are critically dependent on type 1 interferon (show IFNA Proteins) (IFN-1) signaling, which triggers mitochondrial accumulation of full-length Bid.

  2. In the present study, we identified the proapoptotic Bcl-2 (show BCL2 Proteins) family protein Bid as a positive regulator of mutant SOD1 (show SOD1 Proteins)-induced TLR-nuclear factor-kappaB (NF-kappaB (show NFKB1 Proteins)) signaling in microglia.

  3. ATM (show ATM Proteins)-BID-MTCH2 (show MTCH2 Proteins) pathway that we have identified plays a critical role in the DDR (show DDR1 Proteins) via regulation of mitochondrial metabolism.

  4. DRP1 (show CRMP1 Proteins)-dependent apoptotic mitochondrial fission occurs independently of BAX (show BAX Proteins), BAK (show BAK1 Proteins) and APAF1 (show APAF1 Proteins) to amplify cell death by BID and oxidative stress.

  5. A phosphorylation-deficient mutant of BID, MTCH2 (show MTCH2 Proteins)'s ligand, induces an increase in OXPHOS, but with higher ROS (show ROS1 Proteins) and reduced ATP levels than Mtch2 (show MTCH2 Proteins) loss, and is associated with hypersensitivity to irradiation.

  6. Motifs of VDAC2 (show VDAC2 Proteins) required for mitochondrial Bak (show BAK1 Proteins) import and tBid-induced apoptosis.

  7. BID protein suppresses p38 (show CRK Proteins) activity and induce malignant cell transformation of hepatocytes.

  8. compare membrane permeabilization by Bax (show BAX Proteins) activated by either cBid [cleaved Bid (p7 and p15 (show CDKN2B Proteins))] or Bim (show BCL2L11 Proteins) and examine the role of membrane lipids in the recruitment and activation of these three Bcl-2 (show BCL2 Proteins) pro-apoptotic proteins

  9. Hepatocyte Bid suppression is critical for the resistance to the lethal effects of Fas (show FAS Proteins) activation. Fas (show FAS Proteins) signaling induces differential activation of non-canonical interleukin-1beta maturation, amplified in the absence of apoptotic Bid in hepatocytes.

  10. Data demonstrate a new role for Bid as a mediator of astrocyte activation during neuroinflammation, and suggest that Bid activation may contribute to non-cell autonomous motoneuron degeneration in amyotrophic lateral sclerosis

Pig (Porcine) BH3 Interacting Domain Death Agonist (BID) interaction partners

  1. Bid and Bax (show BAX Proteins) are signal transduction factors in granulosa cells and play proapoptotic roles.

BID Protein Profile

Protein Summary

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)\; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Alternative names and synonyms associated with BID

  • BH3 interacting domain death agonist (BID)
  • BH3 interacting domain death agonist (bida)
  • BH3 interacting domain death agonist (bid)
  • BH3 interacting domain death agonist (Bid)
  • BH3 interacting domain death agonist-like (LOC100355991)
  • BH3-interacting domain death agonist-like (LOC100730546)
  • 2700049M22Rik protein
  • AI875481 protein
  • AU022477 protein
  • bid protein
  • DKFZp469E066 protein
  • FP497 protein
  • si:ch211-238n5.6 protein
  • xbid protein

Protein level used designations for BID

BH3 interacting domain death agonist , BH3-interacting domain death agonist , BID isoform ES(1b) , BID isoform L(2) , BID isoform Si6 , Human BID coding sequence , apoptic death agonist , desmocollin type 4 , p22 BID , apoptotic death agonist BID

458635 Pan troglodytes
486607 Canis lupus familiaris
559425 Danio rerio
724076 Xenopus laevis
782484 Bos taurus
100036674 Xenopus (Silurana) tropicalis
100173269 Pongo abelii
637 Homo sapiens
12122 Mus musculus
64625 Rattus norvegicus
100683675 Canis lupus familiaris
100728186 Cavia porcellus
594852 Sus scrofa
395236 Gallus gallus
510373 Bos taurus
100355991 Oryctolagus cuniculus
100730546 Cavia porcellus
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