Direct IAP-binding protein with low pI / second mitochondria-derived activator of caspase (Smac / DIABLO) promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. SMAC / DIABLO acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Smac / DIABLO is ubiquitously expressed with highest expression in testis.
Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Precaution of Use
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.