anti-Human FADD antibody for Western Blotting

Recommended FADD Antibody (supplied by: Log in to see )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • Fas (TNFRSF6)-associated via death domain
  • FADD
  • Fadd
Epitope
C-Term
32
29
26
20
19
17
14
9
7
6
5
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
217
81
38
11
3
2
Host
Rabbit
171
98
Clonality
Polyclonal
Conjugate
This FADD antibody is un-conjugated
11
10
9
7
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
238
144
86
43
29
15
15
7
5
4
4
3
1
1
Options
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Catalog No. ABIN2792110
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.055029 ABIN317514 EIA IHC (p) WB Mouse IgG2b AA 1-208, N-Term Log in to see J1D2 3
3.055029 ABIN222894 IP WB Rabbit IgG Log in to see Polyclonal 3
3.055029 ABIN395764 WB Mouse IgG1 lambda AA 109-208 Log in to see 3A12 5
3.055029 ABIN1881331 WB Rabbit AA 106-135, Center Log in to see Polyclonal 5
3.055029 ABIN967945 IF IP IHC WB Mouse IgG1 AA 94-208 Log in to see 1-FADD 5
3.055029 ABIN967944 IF IP IHC WB Mouse IgG1 AA 94-208 Log in to see 1-FADD 5
3.055029 ABIN967524 IP WB Mouse IgG1, kappa Log in to see A66-2 2
3.055029 ABIN967598 WB Mouse IgG1, kappa Ser194, pSer194 Log in to see J119-857-36 4
3.055029 ABIN3043202 WB Rabbit IgG AA 174-189, C-Term Log in to see Polyclonal
3.055029 ABIN1531271 IHC ELISA WB Rabbit IgG pSer194 Log in to see Polyclonal
3.055029 ABIN3182514 ELISA IHC WB Rabbit IgG pSer194 Log in to see Polyclonal
3.055029 ABIN3184575 ELISA IHC WB Rabbit IgG Tyr397 Log in to see Polyclonal
3.055029 ABIN316073 IHC (p) IHC ELISA WB Mouse IgG2b AA 1-208 Log in to see J1D2
3.055029 ABIN306466 ELISA WB Mouse IgG2b, kappa chain Log in to see J1D2 3
3.055029 ABIN1532291 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
3.055029 ABIN2706139 IC IF IHC WB Rabbit Center Log in to see Polyclonal
3.055029 ABIN2463651 IHC ELISA WB Rabbit Log in to see Polyclonal
3.055029 ABIN2453015 FACS WB Mouse IgG1 Log in to see 1C11
3.055029 ABIN1872640 IHC IP WB Rabbit IgG Log in to see Polyclonal
3.055029 ABIN4310044 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal

Top referenced anti-FADD antibody for Western Blotting

Similar anti-FADD Antibodies

Application / Reactivity Human
ELISA 119 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 65 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 38 Antibodies
Immunoprecipitation (IP) 28 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 200 Antibodies

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
Epitope C-Term
(32), (29), (26), (20), (19), (17), (14), (9), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(217), (81), (38), (11), (3), (2)
Host Rabbit
(171), (98)
Clonality
Polyclonal
Conjugate This FADD antibody is un-conjugated
(11), (10), (9), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(238), (144), (86), (43), (29), (15), (15), (7), (5), (4), (4), (3), (1), (1)
Pubmed 1 reference available
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Product Details anti-FADD Antibody

Target Details FADD Application Details Handling ProductDetails: References for anti-FADD antibody (ABIN2792110) Images
Sequence AHLVGALRSC QMNLVADLVQ EVQQARDLQN RSGAMSPMSW NSDASTSEAS
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against FADD. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human FADD

Target Details FADD

Product Details anti-FADD Antibody Application Details Handling ProductDetails: References for anti-FADD antibody (ABIN2792110) Images back to top
Antigen
Alternative Name FADD (FADD Antibody Abstract)
Background The protein encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.
Alias Symbols: GIG3, MORT1
Protein Interaction Partner: CFLAR, CASP10, CASP8, ATG5, ATG12, TNF, TRADD, UBC, RIPK1, FAS, TNFSF10, SPOP, TNFRSF1A, MYD88, TNFRSF10A, TNFRSF10B, MKRN1, RIPK3, CUL3, TRAF2, PARK7, FASLG, LRRK2, IKBKG, BMX, FAF1, EDAR, DAPK1, CLIP3, DAXX, TNFAIP3, MAVS, KHDRBS1, TAB1, EZR, TRIM21, IR
Protein Size: 208
Molecular Weight 23 kDa
Gene ID 8772
NCBI Accession NM_003824, NP_003815
UniProt Q13158
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-FADD Antibody Target Details FADD Handling ProductDetails: References for anti-FADD antibody (ABIN2792110) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 208 AA

Restrictions For Research Use only

Handling

Product Details anti-FADD Antibody Target Details FADD Application Details ProductDetails: References for anti-FADD antibody (ABIN2792110) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-FADD antibody (ABIN2792110)

Product Details anti-FADD Antibody Target Details FADD Application Details Handling Images back to top
Product cited in:

Thomas, Henson, Reed, Salsbury, Thorburn: "Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD." in: The Journal of biological chemistry, Vol. 279, Issue 31, pp. 32780-5, 2004

Images

Product Details anti-FADD Antibody Target Details FADD Application Details Handling ProductDetails: References for anti-FADD antibody (ABIN2792110) back to top
Supplier Images
Western Blotting (WB) image for anti-FADD antibody (Fas (TNFRSF6)-Associated Via Death Domain) (C-Term) (ABIN2792110) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-FADD antibody (Fas (TNFRSF6)-Associated Via Death Domain) (C-Term) (ABIN2792110) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (C-Term) antibody (Image 2)