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anti-Rat (Rattus) FADD antibody for Immunoprecipitation

Recommended FADD Antibody (supplied by: Log in to see )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
  • MORT1
  • Mort1
  • Mort1/FADD
  • TNFRSF6
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
168
69
31
6
3
3
1
Host
Rabbit
169
54
Clonality
Polyclonal
Conjugate
This FADD antibody is un-conjugated
9
8
7
5
5
5
3
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
189
110
73
19
17
13
13
7
5
4
3
2
1
1
Supplier
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Catalog No. ABIN222894
$ 304.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009004611 ABIN126986 IP WB Rabbit Log in to see Polyclonal
0.0009004611 ABIN1584432 IP IHC ELISA WB Rabbit Log in to see Polyclonal
0.0009004611 ABIN1002282 IP WB Rabbit IgG Log in to see Polyclonal
0.0009004611 ABIN2988843 IP IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-FADD antibody for Immunoprecipitation

Similar anti-FADD Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Monkey
Western Blotting (WB) 154 Antibodies 65 Antibodies 20 Antibodies 7 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 22 Antibodies 5 Antibodies 5 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 6 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 55 Antibodies 39 Antibodies 10 Antibodies 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(168), (69), (31), (6), (3), (3), (1)
Host Rabbit
(169), (54)
Clonality
Polyclonal
Conjugate This FADD antibody is un-conjugated
(9), (8), (7), (5), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP), Western Blotting (WB)
(189), (110), (73), (19), (17), (13), (13), (7), (5), (4), (3), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-FADD Antibody

Target Details FADD Application Details Handling References for anti-FADD Antibody (ABIN222894) Images
Blocking Peptide Blocking peptide for this product available: ABIN412728
Specificity The antibody detects an ~28 kDa band, corresponding to the expected molecular mass of FADD on immunoblots.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 128 of human FADD
Isotype IgG

Target Details FADD

Product Details anti-FADD Antibody Application Details Handling References for anti-FADD Antibody (ABIN222894) Images back to top
Antigen
Alternative Name FADD (FADD Antibody Abstract)
Background Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.
Synonyms: FAS-associated death domain protein, GIG3, MGC8528, MORT1
Gene ID 8772
UniProt Q13158
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, TLR Signaling

Application Details

Product Details anti-FADD Antibody Target Details FADD Handling References for anti-FADD Antibody (ABIN222894) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL) and can also be used in Immunoprecipitation.
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-FADD Antibody Target Details FADD Application Details References for anti-FADD Antibody (ABIN222894) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) affinity purified rabbit anti-FADD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-FADD Antibody (ABIN222894)

Product Details anti-FADD Antibody Target Details FADD Application Details Handling Images back to top
Product cited in:

Jin, Ojcius, Sun, Dong, Luo, Mao, Yan: "Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways." in: Infection and immunity, Vol. 77, Issue 2, pp. 799-809, 2009

Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: "Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22425-36, 2005

Piazzolla, Meissl, Kucerova, Rubiolo, Baccarini: "Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling." in: The Journal of cell biology, Vol. 171, Issue 6, pp. 1013-22, 2005

Images

Product Details anti-FADD Antibody Target Details FADD Application Details Handling References for anti-FADD Antibody (ABIN222894) back to top
Supplier Images
Western Blotting (WB) image for anti-FADD antibody (Fas (TNFRSF6)-Associated Via Death Domain) (ABIN222894) Western blot analysis of FADD expression with Jurkat cell lysates (Lane 1, 2).