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anti-Rat (Rattus) FASL antibody for Functional Studies

Recommended FASL Antibody (supplied by: Log in to see )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand (TNF superfamily, member 6)
  • Fas (TNF receptor superfamily, member 6)
  • fas ligand
  • faslg
  • FAS
  • FASLG
  • fas
  • LOC100344073
  • Fasl
  • Faslg
Reactivity
Mouse (Murine), Rat (Rattus)
364
172
89
22
7
5
5
3
3
2
1
1
Host
Hamster
200
175
48
32
29
8
1
Clonality
Monoclonal
Conjugate
This FASL antibody is un-conjugated
41
28
24
9
9
7
6
6
6
5
5
5
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
287
215
97
82
73
63
37
32
28
25
13
12
10
10
5
4
3
3
2
2
1
1
1
1
1
1
1
Supplier
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Supplier Product No.
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Catalog No. ABIN614575
$ 621.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2478838 Func FACS Hamster IgG Log in to see MFL4 3
1 ABIN1819960 Func FACS Hamster IgG Log in to see MFL4
1 ABIN1820311 Func FACS Hamster IgG Log in to see

Top referenced anti-FASL antibody for Functional Studies

Similar anti-FASL Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies 3 Antibodies
ELISA 8 Antibodies 10 Antibodies
Flow Cytometry (FACS) 38 Antibodies 116 Antibodies
Functional Studies (Func) 4 Antibodies 9 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 9 Antibodies
Immunofluorescence (IF) 1 Antibodies 6 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 14 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 44 Antibodies
Immunochromatography (IC) 3 Antibodies

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(364), (172), (89), (22), (7), (5), (5), (3), (3), (2), (1), (1)
Host Hamster
(200), (175), (48), (32), (29), (8), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FASL antibody is un-conjugated
(41), (28), (24), (9), (9), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(287), (215), (97), (82), (73), (63), (37), (32), (28), (25), (13), (12), (10), (10), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FASL Antibody

Target Details FASL Application Details Handling References for anti-FASL Antibody (ABIN614575) Images
Specificity Recognizes both Mouse and Rat CD178. Clone MFL4 is reported to block CD178/CD95 induced apoptosis.
Purification Affinity Chromatography on Protein G
Endotoxin Level Low Endotoxin
Immunogen B6 Mouse FasL/BHK cells
Clone MFL4
Isotype IgG

Target Details FASL

Product Details anti-FASL Antibody Application Details Handling References for anti-FASL Antibody (ABIN614575) Images back to top
Antigen
Alternative Name CD178 / Fas Ligand (FASL Antibody Abstract)
Background CD178, otherwise known as Fas Ligand/ CD95L, a 40 kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
Gene ID 14103
NCBI Accession NP_034307
UniProt P41047
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FASL Antibody Target Details FASL Handling References for anti-FASL Antibody (ABIN614575) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FASL Antibody Target Details FASL Application Details References for anti-FASL Antibody (ABIN614575) Images back to top
Concentration 1.0 mg/mL
Buffer PBS without preservatives
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted at -20 °C.

References for anti-FASL Antibody (ABIN614575)

Product Details anti-FASL Antibody Target Details FASL Application Details Handling Images back to top
Background publications

Watanabe, Yoshida, Shirai, Yamori, Yagita, Itoh, Chiba, Kita, Wakatsuki: "Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 5, pp. 2188-99, 2002

Trinité, Voisine, Yagita, Josien: "A subset of cytolytic dendritic cells in rat." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 8, pp. 4202-8, 2000

Kayagaki, Yamaguchi, Nagao, Matsuo, Maeda, Okumura, Yagita: "Polymorphism of murine Fas ligand that affects the biological activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3914-9, 1997