You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Zebrafish (Danio rerio) KRT18 antibody for Immunohistochemistry (Frozen Sections)

Recommended KRT18 Antibody (supplied by: Log in to see )

Antigen
Keratin 18 (KRT18) Antibodies
  • cb83
  • CK18
  • CYK18
  • dapk1
  • DreK18
  • K18
  • Krt1-18
  • krt18
  • KRT18
  • krtt1c6
  • MGC64569
  • MGC75922
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • zgc:66015
Reactivity
Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout, Zebrafish (Danio rerio)
898
165
142
56
54
32
28
25
19
19
19
17
12
12
7
7
7
5
3
3
3
3
1
1
1
Host
Mouse
664
268
10
9
6
2
Clonality
Monoclonal
Conjugate
This KRT18 antibody is un-conjugated
50
47
21
18
18
17
14
14
14
14
14
14
14
14
14
14
11
11
4
3
3
3
3
3
3
2
2
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
625
446
377
339
311
272
251
193
164
34
18
12
11
9
3
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN111183
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008825491 ABIN1106920 IHC (fro) FACS IF IHC (p) WB Mouse IgG1 Log in to see DE-K18 4
0.0008825491 ABIN1106918 IHC (fro) FACS IF WB Mouse IgG1 Log in to see RGE53 9
0.0008825491 ABIN335218 ICC FACS IHC (fro) IHC WB Mouse IgG1 Log in to see RGE53 8
0.0008825491 ABIN335330 ICC FACS IHC (fro) IHC WB Mouse IgG1 Log in to see RGE53 8
0.0008825491 ABIN4302638 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 405 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302639 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 488 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302640 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 647 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302641 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 700 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302626 FACS ICC IF IHC IHC (fro) WB DyLight 488 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302629 FACS ICC IF IHC IHC (fro) WB DyLight 405LS Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302631 FACS ICC IF IHC IHC (fro) WB DyLight 680 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302603 FACS ICC IF IHC IHC (fro) WB Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302607 FACS ICC IF IHC IHC (fro) WB DyLight 350 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302610 FACS ICC IF IHC IHC (fro) WB DyLight 405 Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302613 FACS ICC IF IHC IHC (fro) WB PE Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302616 FACS ICC IF IHC IHC (fro) WB PerCP Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302619 FACS ICC IF IHC IHC (fro) WB Allophycocyanin Mouse IgG1 Log in to see RGE53
0.0008825491 ABIN4302622 FACS ICC IF IHC IHC (fro) WB DyLight 755 Mouse IgG1 Log in to see RGE53

Top referenced anti-KRT18 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-KRT18 Antibodies

Application / Reactivity Human Cow (Bovine) Dog (Canine) Hamster Mouse (Murine) Pig (Porcine) Rat (Rattus) Sheep (Ovine) Trout Zebrafish (Danio rerio)
Western Blotting (WB) 593 Antibodies 14 Antibodies 34 Antibodies 21 Antibodies 130 Antibodies 45 Antibodies 81 Antibodies 4 Antibodies 3 Antibodies 20 Antibodies
Light Microscopy (LM) 3 Antibodies
Immunoprecipitation (IP) 157 Antibodies 3 Antibodies 21 Antibodies 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 439 Antibodies

General

Antigen Keratin 18 (KRT18) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout, Zebrafish (Danio rerio)
(898), (165), (142), (56), (54), (32), (28), (25), (19), (19), (19), (17), (12), (12), (7), (7), (7), (5), (3), (3), (3), (3), (1), (1), (1)
Host Mouse
(664), (268), (10), (9), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This KRT18 antibody is un-conjugated
(50), (47), (21), (18), (18), (17), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (11), (11), (4), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(625), (446), (377), (339), (311), (272), (251), (193), (164), (34), (18), (12), (11), (9), (3), (2), (2), (1), (1), (1)
Pubmed 12 references available
Supplier Log in to see

Product Details anti-KRT18 Antibody

Target Details KRT18 Application Details Handling References for anti-KRT18 Antibody (ABIN111183) Images
Specificity Ks 18.04 represents an excellent marker to discriminate simple epithelia from those of different origin. Tumors specifically detected: all adenocarcinoma, mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma. Polypeptide reacting: Mr 45 000 polypeptide (human keratin K18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia. Reactivities on cultured cell lines (tested so far): HeLa and MCF-7
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat, Bovine, Porcine, Canine, Hamster, Sheep, Fish (Trout) and Zebrafish
Purification Protein A chromatography
Immunogen Human keratin K18 from HeLa cytoskeletal preparation
Clone Ks18-04
Isotype IgG1

Target Details KRT18

Product Details anti-KRT18 Antibody Application Details Handling References for anti-KRT18 Antibody (ABIN111183) Images back to top
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Gene ID 3875
NCBI Accession NP_000215
UniProt P05783
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-KRT18 Antibody Target Details KRT18 Handling References for anti-KRT18 Antibody (ABIN111183) Images back to top
Application Notes Western blot. Immunohistochemistry (dilute 1: 20 with PBS): suitable for cytological material, frozen andparaffin-embedded tissue (for best performance, microwave treatment is recommended). Incubation time: 1h at 37C, extended with paraffin sections (overnight at 2-8C).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details References for anti-KRT18 Antibody (ABIN111183) Images back to top
Reconstitution Restore in 1.0 mL distilled water.
Buffer PBS, pH 7.4, 0.09 % Sodium azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing). Dilute only prior to immediate use.
Storage -20 °C
Storage Comment Store the antiserum at -20 °C (aliquot contents to

References for anti-KRT18 Antibody (ABIN111183)

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling Images back to top
Product cited in:

Zatloukal, Kufferath, Thueringer, Landegren, Zatloukal, Haybaeck: "Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies." in: PLoS ONE, Vol. 9, Issue 5, pp. e96690, 2014

Trowe, Airik, Weiss, Farin, Foik, Bettenhausen, Schuster-Gossler, Taketo, Kispert: "Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter." in: Development (Cambridge, England), Vol. 139, Issue 17, pp. 3099-108, 2012

Sharma, Cantz, Richter, Eckert, Henschler, Wilkens, Jochheim-Richter, Arseniev, Ott: "Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver." in: The American journal of pathology, Vol. 167, Issue 2, pp. 555-64, 2005

Ikenouchi, Matsuda, Furuse, Tsukita: "Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail." in: Journal of cell science, Vol. 116, Issue Pt 10, pp. 1959-67, 2003

Schaffeld, Knappe, Hunzinger, Markl: "cDNA sequences of the authentic keratins 8 and 18 in zebrafish." in: Differentiation; research in biological diversity, Vol. 71, Issue 1, pp. 73-82, 2003

Stumptner, Fuchsbichler, Heid, Zatloukal, Denk: "Mallory body--a disease-associated type of sequestosome." in: Hepatology (Baltimore, Md.), Vol. 35, Issue 5, pp. 1053-62, 2002

Bantel, Ruck, Gregor, Schulze-Osthoff: "Detection of elevated caspase activation and early apoptosis in liver diseases." in: European journal of cell biology, Vol. 80, Issue 3, pp. 230-9, 2001

Gomi, Yokoyama, Fujimoto, Ikeda, Katoh, Itoh, Itohara: "Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions." in: Neuron, Vol. 14, Issue 1, pp. 29-41, 1995

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989

Background publications

Bredt: "Nitric oxide signaling specificity--the heart of the problem." in: Journal of cell science, Vol. 116, Issue Pt 1, pp. 9-15, 2002

Moll, Franke, Schiller, Geiger, Krepler: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983