anti-Human NME1 antibody for Enzyme Immunoassay

Recommended NME1 Antibody (supplied by: Log in to see )

Antigen
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) Antibodies
  • NDK I
  • NDPK I
  • NME1
  • NME1-NME2
  • AWD
  • GAAD
  • NB
  • NBS
  • NDKA
  • NDPK-A
  • NDPKA
  • NM23
  • NM23-H1
  • AL024257
  • NM23-M1
  • NM23A
  • ndpk-b
  • ndpkb
  • nm23-h2
  • nm23b
  • nm23ndk
  • nme1
  • puf
  • nm23ndk-a
  • nme2
  • NDPK-Z1
  • NM23-B
  • NM23-Z1
  • ndpkz1
  • nme2b1
  • NM23-C1
  • NBR-A
  • NBR-B
  • NME1-1
  • T30A10.80
  • T30A10_80
  • CHH
  • RMRPR
  • RRP2
  • nucleoside diphosphate kinase
  • non-metastatic cells 1, protein (NM23A) expressed in
  • NME/NM23 nucleoside diphosphate kinase 1
  • NME/NM23 nucleoside diphosphate kinase 2
  • NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
  • nucleoside diphosphate kinase 1
  • RNA component of mitochondrial RNA processing endoribonuclease
  • LOC547870
  • NME1
  • Nme1
  • nme2-b
  • nme2-a
  • nme2b.1
  • NDPK1
  • RMRP
Epitope
AA 102-131, C-Term
22
20
13
13
11
9
9
8
7
7
6
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
292
54
51
14
9
8
6
4
4
3
3
2
2
1
1
Host
Rabbit
145
142
6
2
2
Clonality
Polyclonal
Conjugate
This NME1 antibody is un-conjugated
12
12
8
7
6
6
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
250
125
88
64
40
15
13
12
10
6
6
2
2
1
Supplier
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Catalog No. ABIN5556291
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552299 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
1 ABIN5556290 EIA WB Rabbit Ig Fraction AA 28-57, Middle Region Log in to see Polyclonal
1 ABIN782418 EIA IF IHC (p) IP WB Mouse IgG1 AA 43-153 Log in to see 1D7
1 ABIN1108395 EIA FACS IF IHC (p) WB Mouse IgG1 Log in to see 4B2 1
1 ABIN614434 EIA IF IHC (p) WB Mouse IgG2b Log in to see 4B2
1 ABIN2726925 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

General

Antigen Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) Antibodies
Epitope AA 102-131, C-Term
(22), (20), (13), (13), (11), (9), (9), (8), (7), (7), (6), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(292), (54), (51), (14), (9), (8), (6), (4), (4), (3), (3), (2), (2), (1), (1)
Host Rabbit
(145), (142), (6), (2), (2)
Clonality
Polyclonal
Conjugate This NME1 antibody is un-conjugated
(12), (12), (8), (7), (6), (6)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(250), (125), (88), (64), (40), (15), (13), (12), (10), (6), (6), (2), (2), (1)
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Product Details anti-NME1 Antibody

Target Details NME1 Application Details Handling Images
Specificity This antibody recognizes NDP kinase A (NME1) at C-term. Other speci9es not tested.
Cross-Reactivity (Details) Species reactivity (expected):Rat.
Species reactivity (tested):Human.
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 102-131aa) of human NDP kinase A
Isotype Ig Fraction

Target Details NME1

Product Details anti-NME1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name NDP Kinase A (NME1 Antibody Abstract)
Background The NME1 gene was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Function: Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein- coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Cellular Location: Cytopla sm. Nucleus. Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA. Tissue Location: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.Synonyms: GAAD, Granzyme A-activated DNase, NDPKA, NM23, NME1, Nucleoside diphosphate kinase A, nm23-H1
Molecular Weight 17149 Da
Gene ID 4830
NCBI Accession NP_000260
Research Area Cancer, Kinases/Phosphatases, Transcription Factors
Pathways Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process

Application Details

Product Details anti-NME1 Antibody Target Details NME1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-NME1 Antibody Target Details NME1 Application Details Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.