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Browse our anti-SET (SET) Antibodies

Full name:
anti-SET Nuclear Oncogene Antibodies (SET)
On are 10 SET Nuclear Oncogene (SET) Antibodies from 5 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 13 SET products are currently listed.
2PP2A, 2610030F17Rik, 5730420M11Rik, AA407739, I-2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, StF-IT-1, TAF-I, TAF-IBETA

Most Popular Reactivities for anti-SET (SET) Antibodies

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anti-Human SET Antibodies:

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anti-Rat (Rattus) SET Antibodies:

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Top referenced anti-SET Antibodies

  1. Human Polyclonal SET Primary Antibody for WB - ABIN4620361 : von Lindern, van Baal, Wiegant, Raap, Hagemeijer, Grosveld: Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene. in Molecular and cellular biology 1992 (PubMed)
    Show all 12 references for ABIN4620361

  2. Human Polyclonal SET Primary Antibody for WB - ABIN374103 : Ruiz, Kim, Sartor, Haller et al.: 15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through ... in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against SET Interaction Partners

Human SET Nuclear Oncogene (SET) interaction partners

  1. This review summarizes and discusses the general mechanisms of H3K4 methylation, and how the six main enzymes from the SET/MLL (show MLL Antibodies) family (responsible for H3K4me1/me2 (show CELSR1 Antibodies)/me3 (show ME3 Antibodies)) function in hematopoiesis and in hematologic malignancies. [review]

  2. identification of the oncoprotein SET as a major cellular factor whose binding with p53 (show TP53 Antibodies) is dependent on C-terminal domain acetylation status

  3. Data indicate that SET protein as a direct target of microRNA miR (show MLXIP Antibodies)-125b, and the downregulation of SET, observed during tumor migration, was affected by the overexpression of miR125b.

  4. significance of SET/I2PP2A-mediated PP2A (show PPP2R4 Antibodies) and non-PP2A (show PPP2R4 Antibodies) pathways in polycystic ovary syndrome

  5. Data show that downregulating proto-oncogene (show RAB1A Antibodies) protein Akt (p-Akt (show AKT1 Antibodies)) by inhibiting PP2A (show PPP2R4 Antibodies) inhibitor SET-mediated protein phosphatase 2A (PP2A (show PPP2R4 Antibodies)) inactivation determined the pro-apoptotic effects of EMQA and paclitaxel combination treatment.

  6. Data suggest a critical role for the I2PP2A protein (SET)-protein phosphatase-2A (PP2A (show PPP2R4 Antibodies)) signaling axis in Pten (show PTEN Antibodies) protein (Pten (show PTEN Antibodies)) deficient castration resistant prostate cancer (CRPC) progression.

  7. Data show that the biogical effect of inhibitor-2 of protein phosphatase-2A (SET) on proliferation and invasion was mediated by the inhibition of the protein phosphatase 2A (PP2A (show PPP2R4 Antibodies)).

  8. Both SET protein levels (and BACE1 (show BACE Antibodies)) were increased in Down syndrome patients.

  9. SET interacts with the Kruppel-associated box (KRAB)-associated co-repressor KAP1 (show CDKN3 Antibodies), and its overexpression results in the sustained retention of KAP1 (show CDKN3 Antibodies) and Heterochromatin protein 1 (HP1 (show DEFA1 Antibodies)) on chromatin

  10. the results of the present study demonstrated that SET was associated with paclitaxel resistance in MCF-7/PTX cells, and that paeonol reversed paclitaxel resistance in MCF-7/PTX cells by downregulating the activity of the SET/PP2A (show PPP2R4 Antibodies)/Akt (show AKT1 Antibodies) pathway.

Mouse (Murine) SET Nuclear Oncogene (SET) interaction partners

  1. Data suggest a critical role for the I2PP2A protein (SET)-protein phosphatase-2A (PP2A (show PPP2R2B Antibodies)) signaling axis in Pten (show PTEN Antibodies) protein (Pten (show PTEN Antibodies)) deficient castration resistant prostate cancer (CRPC) progression.

  2. The presence of full-length SET in the neuronal cytoplasm is sufficient to impair PP2A (show PPP2R2B Antibodies) methylation and activity, leading to tau hyperphosphorylation.

  3. SET/PP2A (show PPP2R2B Antibodies) system regulates testosterone production in ovarian follicles in vitro.

  4. SET played a positive role in regulating ovarian androgen biosynthesis by enhancing the transcription of steroidogenic enzymes CYP17A1 (show CYP17A1 Antibodies) and HSD3B2 (show HSD3B2 Antibodies), which maybe contribute to the hyperandrogenism in polycystic ovary syndrome

  5. study found SET, a putative oncogene (show RAB1A Antibodies) was significantly downregulated in a bisphenol A dose-dependent manner; from gene network analysis, SET is predicted to communicate with other genes including CYP17 (show CYP17A1 Antibodies), which is involved in biosynthesis and metabolism of sex-hormones

  6. Our results suggest that the increased I(2)(PP2A (show PPP2R2B Antibodies)) may trigger apoptosis by p53 (show TP53 Antibodies) upregulation, but due to simultaneous activation of Akt (show AKT1 Antibodies), the neurons are aborted from the apoptotic pathway.

  7. SET is an important regulator of chromosome condensation (show RCC1 Antibodies)/decondensation and that disruption of the MCPH1 (show MCPH1 Antibodies)-SET interaction might be important for the pathogenesis of primary microcephaly

  8. By a novel molecular mechanism, apolipoprotein (apo)E (show APOE Antibodies)/peptide enhances protein phosphatase 2A (PP2A (show PPP2R2B Antibodies)) activity within a cell by binding/forming a complex with SET, reducing the amount of SET available to inhibit PP2A (show PPP2R2B Antibodies), signaling, and inflammatory response.

  9. These studies indicated that the TAF (show TAF8 Antibodies)-Ialpha promoter is under the control of Sp1 (show SP1 Antibodies).(TAF (show TAF8 Antibodies)-Ialpha )

  10. results from differential proteome analysis report a role for SET in Galpha(12 (show GNA12 Antibodies))-mediated signaling pathways and a role for Galpha(12 (show GNA12 Antibodies)) in the regulation of the leukemia-associated SET-protein expression

SET Antigen Profile

Antigen Summary

The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SET

  • SET translocation (LOC403555) antibody
  • SET nuclear oncogene (SET) antibody
  • SET nuclear oncogene (Set) antibody
  • 2PP2A antibody
  • 2610030F17Rik antibody
  • 5730420M11Rik antibody
  • AA407739 antibody
  • I-2PP2A antibody
  • I2PP2A antibody
  • IGAAD antibody
  • IPP2A2 antibody
  • PHAPII antibody
  • StF-IT-1 antibody
  • TAF-I antibody
  • TAF-IBETA antibody

Protein level used designations for SET

protein phosphatase 2A inhibitor 2-like , HLA-DR-associated protein II , SET translocation (myeloid leukemia-associated) , Template-Activating Factor-I, chromatin remodelling factor , inhibitor of granzyme A-activated DNase , inhibitor-2 of protein phosphatase-2A , phosphatase 2A inhibitor I2PP2A , protein SET , protein phosphatase type 2A inhibitor , SET translocation , template-activating factor I , I-2PP2A , TAF-I , liver regeneration-related protein LRRGR00002

403555 Canis lupus familiaris
6418 Homo sapiens
56086 Mus musculus
307947 Rattus norvegicus
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