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anti-Mouse (Murine) COX2 Antibodies:
anti-Rat (Rattus) COX2 Antibodies:
anti-Human COX2 Antibodies:
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Human Monoclonal COX2 Primary Antibody for WB - ABIN283213
Cheng, Whitehead, Hachinski, Cechetto: Effects of pyrrolidine dithiocarbamate on beta-amyloid (25-35)-induced inflammatory responses and memory deficits in the rat. in Neurobiology of disease 2006
Tested the roles of COX-2 and EP receptors in VEGF-C (show VEGFC Antibodies) and -D production by a highly metastatic COX-2 expressing murine breast cancer cell line C3L5.
Rickettsia conorii infection of susceptible mice, therefore, results in selective regulation of the expression of HO-1 (show HMOX1 Antibodies) and COX-2 in a manner dependent on the target host tissue's cellular environment and the propensity of infection with rickettsiae.
Data suggest that physical exercise attenuates age-related changes in mitochondrial COX biogenesis and p53 activity targeting SCO2 and mitochondria, and thereby induces antisenescent and protective effects in cardiac muscle.
Cytochrome c oxidase subunit II is inactivated by mutant SOD1 (show SOD1 Antibodies) in motor neurons; this inactivation requires nitric oxide.
Data suggest that the binding of proteins such as cytochrome c oxidase subunit II to epidermal growth factor (show EGF Antibodies) receptors may positively regulate survival pathways that contribute to oncogenesis.
A lifetime absence of COX-2 produces multiple changes in brain lipid composition. These changes may be related to reported changes in fatty acid kinetics and in resistance to neuroinflammation and excitotoxicity in the COX-2(-/-) mouse
Activation of the signaling pathway is responsible for keratinocyte proliferation and reveal a positive feedback loop between COX-2 and PGE2.
The gene expression of Cox2 in adipocytes was studied.
co-ordinated post-translational modifications of p65 (show NFkBP65 Antibodies) and histone H3 (show HIST3H3 Antibodies) involving phosphorylation and acetylation drive COX-2-dependent transcriptional activation of the MMP-9 (show MMP9 Antibodies) gene in response to challenge of macrophages with M. avium.
aberrant renin (show REN Antibodies)-producing cells in Cx40 (show GJA5 Antibodies)-deficient kidneys express significant amounts of COX-2
Data indicate that the proton-pumping pathway of heart cytochrome c (show CYCS Antibodies) oxidase includes a hydrogen-bond network and a water channel (show AQP4 Antibodies) located in tandem between the positive and negative side of the mitochondrial membrane.
Study suggests that His503 is involved in the proton supply to the D-path as a proton acceptor in cytochrome c (show CYCS Antibodies) oxidase.
Data suggest that the axial Met residue moderately increased the redox potential of the Cu(A) site in cytochrome c (show CYCS Antibodies) oxidase.
Studies indicate that heart cytochrome c (show CYCS Antibodies) oxidase subunits I, II and III are encoded by the mitochondrial genome.
extensive pre- and intrapartal rise of COX (show COX7A1 Antibodies)-II expression in bovine placentomes with a 70-100-fold increase of COX (show COX7A1 Antibodies)-II-mRNA levels
B1 receptors are coupled to COX2 (show PTGS2 Antibodies) in causing endothelium-independent contractions in endotoxin-treated pig coronary arteries
Expression of COX-2 (show PTGS2 Antibodies) was strongest in gilts with acute endometritis, but did not differ between those with chronic endometritis and normal endometrium.
Pretreatment of cells with selective COX-2 blocker etodolac markedly inhibited ICl.
Safflower injection may attenuate lung ischemia/reperfusion injury through inhibiting cyclooxygenase-2 (show PTGS2 Antibodies) expression.
The RNA interference targeting COX-2 can effectively inhibit the expression of COX-2 and MMP-2 (show MMP2 Antibodies) in IL-1alpha stimulated rabbit corneal stromal cells in vitro.
inhibitory effects of 17-AAG (show MPG Antibodies) on PGE2 levels in HT-29 colorectal cancer cells were mediated through modulating COX-2 and 15-PGDH (show HPGD Antibodies) expression.
The sequencing analysis revealed the presence of 17 variants, mostly causing non-synonymous changes in conserved amino acid residues, typically distributed in the MT-CO2 gene of MUTYH (show MUTYH Antibodies)-associated polyposis patients (P < 0.0001), who frequently carried the hot spot m.7763G>A variant.
Results find that COA6 associates with COX2 and is crucial for its maturation and complex IV biogenesis. Also, COA6 interacts with the copper chaperone SCO1 (show SCO1 Antibodies) which indicates that COA6 is intrinsically involved in the copper delivery process for COX2.
Mutational analysis show a novel MTCO2 mutation 8249G>A pathogenic variation in Tunisian patients with mitochondrial myopathy.
We also detected in 4 asthenospermic patients a double novels mutations, the first was found in COXII gene (m.8021 G/A) that was absent in normospermic infertile men.
The presence of a non-synonymous variation in the COII strongly correlated with poor survival in patients with cytogenetically normal acute myeloid leukemia (show BCL11A Antibodies).
Protein modeling revealed loss of function mutations of ND6 (show MT-ND6 Antibodies) and COX (show COX8A Antibodies)-II proteins in malignant vs benign tumors
COX-2 expression played an essential role in the proliferation and metastasis of tongue cancer.
Novel COII mutations responsible for maternally inherited nonsyndromic hearing loss
The apoptotic index of pulmonary vascular endothelial cells was negatively correlated with COXII expression in patients with chronic obstructive pulmonary disease.
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
cytochrome c oxidase subunit II
, cytochrome c oxidase subunit ii
, cytochrome C oxidase subunit II
, PGH synthase 2
, PHS II
, cyclooxygenase 2
, prostaglandin G/H synthase 2
, prostaglandin H2 synthase 2