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anti-Human Adenosine A2b Receptor Antibodies:
anti-Rat (Rattus) Adenosine A2b Receptor Antibodies:
anti-Mouse (Murine) Adenosine A2b Receptor Antibodies:
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Human Polyclonal Adenosine A2b Receptor Primary Antibody for ELISA, ICC - ABIN4278366
Ren, Lin, Cao, Yang, Lu, Liu, Chen, Yang, Tian, Wang, Li, Wang, Chen, Ji, Zhang: CD73 is associated with poor prognosis in HNSCC. in Oncotarget 2016
activation of PPARalpha (show PPARA Antibodies) promoted angiogenesis just as activation of A2B receptors through an epoxide dependent mechanism
mRNA for adenosine A(1), A(2A), A(2B (show ADRA2B Antibodies)), and A(3) receptors was expressed in arterioles and venules. Protein for A(1), A(2A), and A(2B (show ADRA2B Antibodies)), but not A(3), was detected in both microvessel types and was further demonstrated on vascular endothelial cells
findings suggest that hypoxia, through HIF1A (show HIF1A Antibodies), contributes to the development and progression of pulmonary fibrosis through its regulation of ADORA2B expression on alternatively activated macrophages, cell differentiation, and production of profibrotic mediators
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS (show ROS1 Antibodies) production in colorectal cancer cells via adenosine receptor-independent mechanism.
the effects of TNF-alpha (show TNF Antibodies) were investigated on the expression/responsiveness of the A2B adenosine receptor (A2BAR), a Gs-coupled receptor that promotes mesenchymal stem cell (MSC (show MSC Antibodies)) differentiation into osteoblasts.
Actinin (show ACTN1 Antibodies)-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression
cells lacking A2b do not respond in this manner to hypoxia or ATP but transfection of A2b restores this response, that Epac1 (show RAPGEF3 Antibodies) is critically involved, and that Rap1B (show RAP1B Antibodies) is important for the relative positioning of the centrosome and nucleus.
Studies show that A2b receptor is overexpressed in various tumor lines and biopsies from patients with different cancers. This suggests that A2b receptor can be used by tumor cells to promote progression. [review]
Findings suggest that, in obese status, the lower expression level of A2bAR, KLF4, and KLF15 of visceral adipose tissue may correlate with obese-dyslipidemia induced inflammation in Uygur population.
erythrocyte AMP-activated protein kinase (show PRKAA2 Antibodies) was activated in humans at high altitude. It is a key protein functioning downstream of the A2B adenosine receptor, phosphorylating and activating BPG mutase and thus inducing 2,3-BPG production and O2 release from erythrocytes.
A2B receptor activation is critically required for the stimulatory effect of adenosine on IL-10 (show IL10 Antibodies) production and suppression of nitric oxide release.
Data show that ADORA2B mRNA and protein were significantly up-regulated in oral squamous cell carcinoma (OSCC) and that ADORA2B controls cellular proliferation via HIF-1alpha (show HIF1A Antibodies) activation, suggesting it may be a key regulator of tumoral progression in OSCCs.
activation of adenosine A2B receptors on myeloid cells caused nociceptor hyperexcitability and promoted chronic pain via soluble IL-6 (show IL6 Antibodies) receptor trans-signaling.
It has been reported that signaling through hepatocellular Adora2b adenosine receptors dampens IR injury of the liver.
Diabetes resulted in an increased A2A/A2B receptor expression in coronary arteries which resulted in enhanced A2A/A2B-mediated increase in coronary flow observed in diabetic hearts.
A2B adenosine receptor-induced VEGF production and angiogenesis are involved in myeloid-derived suppressor cells in a mouse melanoma model
Angiotensin II stimulation alters vasomotor response to adenosine in mouse mesenteric artery: role for A1 and A2B adenosine receptors
our results suggest that intestinal epithelial Adora2b signaling provides protection during intestinal inflammation via enhancing mucosal barrier responses.
exposure of DCs to A2BR agonist facilitated gammadelta T cell activation, leading to augmented Th17 responses and progressive EAU development.
IFN-gamma (show IFNG Antibodies) priming of macrophages selectively prevents the induction of the A2bR in macrophages to mitigate sensitivity to adenosine and to prevent this regulatory transition.
These findings implicate that tissue-specific targeting of Adora2b seems to be desirable when using Adora2b agonists to prevent or treat myocardial ischemia.
Purinergic stimulation of cilia beat frequency requires A(2B (show ADRA2B Antibodies)) adenosine receptor activation, likely via protein kinase A-dependent pathway.
It is likely that adenosine acts through A(2B (show ADRA2B Antibodies)) receptors and adenylyl cyclases to stimulate CNGA2 (show CNGA2 Antibodies).
Study reveals presence of adenosine A(2A) and A(2B (show ADRA2B Antibodies)) receptors as well as a role for them in lacrimal gland secretion, and especially in synergy with purinergic and cholinergic stimulation.
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
adenosine receptor A2b
, adenosine A2b receptor
, A2b adenosine receptor
, adenosine receptor A2b-like
, A2b, Rs
, adenosine receptor 2b
, A2B adenosine receptor