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anti-Human CAP1 Antibodies:
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Human Monoclonal CAP1 Primary Antibody for ELISA, WB - ABIN564567
Cauwe, Martens, Van den Steen, Proost, Van Aelst, Blockmans, Opdenakker: Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9. in Experimental cell research 2008
Show all 2 Pubmed References
Human Polyclonal CAP1 Primary Antibody for IF, IP - ABIN950065
Jansen, Collins, Golden, Sokolova, Goode: Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics. in The Journal of biological chemistry 2014
Human Polyclonal CAP1 Primary Antibody for FACS, IF - ABIN523895
Wakeel, Kuriakose, McBride: An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. in Infection and immunity 2009
cap1 regulates cortical actin distribution specifically in the anterior mesendoderm of the zebrafish gastrula.
The requirement of Cap1 for a cellular apical constriction step suggests a conservation of gene function for a cell biological event critical to many developmental processes.
CAP1 (show PRSS8 Antibodies) expression is markedly increased in human glioma and that downregulation of CAP1 (show PRSS8 Antibodies) in tumors may serve as a treatment for glioma patients.
our results indicated that CAP1 (show PRSS8 Antibodies) participated in the molecular pathological process of glioma
a high expression of CAP1 (show PRSS8 Antibodies) is involved in the pathogenesis of EOC, and that the downregulation of CAP1 (show PRSS8 Antibodies) in tumor cells may be a therapeutic target for the treatment of patients with EOC.
This study demonstrated an inverse relationship between CAP1 (show PRSS8 Antibodies) and MMP-9 (show MMP9 Antibodies) expression, high expression of MMP-9 (show MMP9 Antibodies) and low expression of CAP1 (show PRSS8 Antibodies) in those with chronic obstructive pulmonary disease compared with the non-chronic obstructive pulmonary disease group.
CAP1 (show PRSS8 Antibodies) is involved in the brain metastasis in non-small cell lung cancer.CAP1 overexpression is associated with poor prognosis in non-small cell lung cancer patients.
Overexpression of CAP1 (show PRSS8 Antibodies) in monocytes enhanced the resistin (show RETN Antibodies)-induced increased activity of the cAMP-dependent signaling.
results indicate that upregulated expression of CAP1 (show PRSS8 Antibodies) might contribute heavily to the metastasis of hepatocellular carcinoma.
Overexpression of CAP1 (show PRSS8 Antibodies) is associated with breast carcinoma.
CAP1 (show PRSS8 Antibodies) might be a potential molecular targeted therapy for surgery and immune treatment.
overexpression of CAP1 (show PRSS8 Antibodies) in lung cancer cells, particularly at the metastatic stage, may have significant clinical implications as a diagnostic/prognostic factor for lung cancer.
Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Antibodies) and IL-13 (show IL13 Antibodies), down-regulates matriptase (show ST14 Antibodies) as well as prostasin (show PRSS8 Antibodies) through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Antibodies)
a proteolysis-dependent function of activated prostasin (show PRSS8 Antibodies) in hair follicles, dependent on zymogen conversion by matriptase (show ST14 Antibodies).
The claudin-4 (show CLDN4 Antibodies)-mediated chloride conductance can be regulated endogenously by a protease-channel-activating protease 1 (cap1 (show PRSS8 Antibodies)).
Phosphorylation regulates CAP1 function through association with cofilin and actin in order to control the actin cytoskeleton.
HAI-1 (show SPINT1 Antibodies) regulates the activity of activated matriptase (show ST14 Antibodies), whereas HAI-2 (show SPINT2 Antibodies) has an essential role in regulating prostasin (show PRSS8 Antibodies)-dependent matriptase (show ST14 Antibodies) zymogen activation.
a novel inhibitory interaction between CAP1/Prss8 (show PRSS8 Antibodies) and nexin-1 (show SERPINE2 Antibodies), opening the search for specific CAP1/Prss8 (show PRSS8 Antibodies) antagonists that are independent of its catalytic activity
Data indicate that liver-specific serine protease (show F2 Antibodies) prostasin (PRSS8 (show PRSS8 Antibodies)) knockout (LKO) mice develop insulin (show INS Antibodies) resistance associated with the increase in hepatic Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)).
Data indicate that serine protease (show F2 Antibodies) prostasin (CAP1/PRSS8 (show PRSS8 Antibodies)) supports terminal epidermal differentiation through a non-catalytic mechanism.
CAP1 depletion also led to changes in cofilin phosphorylation and localization as well as activation of focal adhesion kinase (FAK) and enhanced cell spreading.
study provides evidence that catalyzing nucleotide exchange on actin monomers via the beta-sheet domain is the most highly conserved function of CAPs (show CAPS Antibodies) from mammals to apicomplexan parasites.
Bovine herpesvirus 1 infection stimulates caspase 1 (show CASP1 Antibodies) activity.
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
adenylyl cyclase-associated protein 1
, CAP, adenylate cyclase-associated protein 1
, CAP, adenylate cyclase-associated protein 1 (yeast)
, adenylyl cyclase-associated protein
, Adenylyl cyclase-associated protein 1
, CAP 1
, adenylyl cyclase-associated CAP protein homolog 1 iae
, adenylyl cyclase-associated CAP protein, yeast homolog 1
, cyclase-associated protein homologue
, channel activating protease 1
, channel-activating protease 1
, serine protease 8