Browse our anti-Neurofibromin 1 (NF1) Antibodies

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anti-Neurofibromin 1 Antibodies (NF1)
On are 123 Neurofibromin 1 (NF1) Antibodies from 17 different suppliers available. Additionally we are shipping Neurofibromin 1 Kits (7) and Neurofibromin 1 Proteins (3) and many more products for this protein. A total of 137 Neurofibromin 1 products are currently listed.
AW494271, CG8318, Dmel\\CG8318, dNF1, E030030H24Rik, fe06d03, hm:zehn0874, Nf-1, nf1, NFNS, VRNF, WSS, wu:fe06d03, zehn0874

Most Popular Reactivities for anti-Neurofibromin 1 (NF1) Antibodies

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anti-Mouse (Murine) Neurofibromin 1 Antibodies:

anti-Human Neurofibromin 1 Antibodies:

anti-Rat (Rattus) Neurofibromin 1 Antibodies:

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Top referenced anti-Neurofibromin 1 Antibodies

  1. Human Polyclonal Neurofibromin 1 Primary Antibody for ICC, IHC (fro) - ABIN152500 : Kuorilehto, Ekholm, Nissinen, Hietaniemi, Hiltunen, Paavolainen, Penttinen, Peltonen: NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006 (PubMed)
    Show all 4 references for 152500

  2. Guinea Pig Monoclonal Neurofibromin 1 Primary Antibody for IHC (p), IP - ABIN152499 : Hisaoka, Hashimoto, Ohguri, Aoki, Okamoto, Tanaka, Okimoto, Nakamura, Ishida: Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasia. in Skeletal radiology 2004 (PubMed)
    Show all 3 references for 152499

  3. Human Polyclonal Neurofibromin 1 Primary Antibody for IF, ELISA - ABIN1534476 : Wallace, Marchuk, Andersen, Letcher, Odeh, Saulino, Fountain, Brereton, Nicholson, Mitchell: Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 2 references for 1534476

  4. Guinea Pig Monoclonal Neurofibromin 1 Primary Antibody for IHC (p), IP - ABIN152498 : Tucker, Riccardi, Brown, Fee, Sutcliffe, Vielkind, Wechsler, Wolkenstein, Friedman: S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas. in Journal of neuroscience research 2011 (PubMed)

More Antibodies against Neurofibromin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Neurofibromin 1 (NF1) interaction partners

  1. Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster.

  2. The N-terminal region of NF1 mediates the interaction with Fak56 and is required for the signaling activity and presynaptic localization of NF1

  3. These results identify dAlk as an upstream activator of dNf1-regulated Ras signaling responsible for several dNf1 defects, and they implicate human Alk (show ALK Antibodies) as a potential therapeutic target in NF1

  4. memory-related functions of Rut (show ADCY5 Antibodies)-AC are both Nf1-dependent and -independent, that Nf1 mediates the formation of two distinct memory components within a single neuron population.

  5. survival of a subset of midline glia cells depends upon direct suppression of the proapoptotic protein HID via the EGF receptor (show EGFR Antibodies)/RAS/MAPK (show MAPK1 Antibodies) pathway

  6. role in insulin (show INS Antibodies)-mediated proliferation of Schneider cells

  7. preliminary crystallographic characterization of a novel segment (homologous to the yeast Sec14p lipid exchange protein) from the neurofibromatosis type 1 protein

  8. Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras

  9. Loss of NF1 can give rise to non-cell-autonomous developmental defects, implicate aberrant Ras-mediated signaling in larval neurons as the primary cause of the NF1 growth deficiency.

  10. Neurofibromin regulates longevity and stress resistance through cAMP regulation of mitochondrial respiration and ROS (show ROS1 Antibodies) production, and NF1 may be treatable using catalytic antioxidants.

Cow (Bovine) Neurofibromin 1 (NF1) interaction partners

  1. DNA variants in the NF1 gene are associated with genetic disposition to bovine spongiform encephalopathy.

Zebrafish Neurofibromin 1 (NF1) interaction partners

  1. study shows negative regulation of Ras (show RAB1A Antibodies) pathway through GAP activity of NF1 limits oligodendrocyte progenitor cell (OPC) proliferation and motility during development; provides insight into oncogenic mechanisms by which NF1 loss contributes to glial tumors

  2. identification and characterization of nf1a and nf1b, orthologues of NF1, that show neural crest and cardiovascular defects resulting from morpholino knockdown, including vascular and cardiac valvular abnormalities

Mouse (Murine) Neurofibromin 1 (NF1) interaction partners

  1. Notch (show NOTCH1 Antibodies) is an Nf1 effector.

  2. Spatially- and temporally-controlled postnatal p53 (show TP53 Antibodies) knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation.

  3. These findings demonstrate a role for Ras-GAP (show RASA1 Antibodies) activity in suppressing the hemogenic potential of the heart and restricting growth of neural crest-derived tissues.

  4. identified p21Ras-dependent hyperphosphorylation of Pu.1 within the nucleus of Nf1 haploinsufficient myelomonocytic osteoclast precursors, providing a novel therapeutic target for the potential treatment of NF1 associated osteolytic manifestations.

  5. Targeted gene deletion of TP53 (show TP53 Antibodies), Pten (show PTEN Antibodies), and NF1 in mouse brain causes glioblastoma.

  6. Data indicated a critical role for Nf1 in regulating multiple mesenchymal stem/progenitor cells functions, including migration and adhesion through both the PI3-K (show PIK3CA Antibodies) and MAPK (show MAPK1 Antibodies) pathways.

  7. this is the first demonstration that different germline NF1 gene mutations differentially dictate neurofibromin function in the brain.

  8. Data suggest that bi-allelic loss of Nf1 induces autonomous adrenal hyper-activity. Nf1 seems involved in the regulation of adrenal cortex function in mice and humans.

  9. FGFR1 (show FGFR1 Antibodies) signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP (show RASA1 Antibodies) neurofibromin during endochondral bone formation

  10. Low levels of NF1 expression were associated with primary and acquired resistance of lung adenocarcinomas to EGFR (show EGFR Antibodies) Thymidine Kinase (show TK1 Antibodies) Inhibitors in patients.

Human Neurofibromin 1 (NF1) interaction partners

  1. The EVH1 domain of Spred1 (show SPRED1 Antibodies) binds to the noncatalytic portion of the GAP-related domain of neurofibromin.

  2. Loss of NF1 gene is associated with malignant peripheral nerve sheath tumors.

  3. Study found that NF1 negatively regulates mTOR (show FRAP1 Antibodies) signaling in a LAMTOR1 (show LAMTOR1 Antibodies)-dependent manner. In addition, the cell growth and survival of NF1-deficient cells have become dependent on hyperactivation of the mTOR (show FRAP1 Antibodies) pathway, and the tumorigenic properties of these cells have become dependent on LAMTOR1 (show LAMTOR1 Antibodies).

  4. Mutations in neurofibromin 1 (NF1) are common in cancer, including melanoma, and targeting NF1-regulated pathways offers potential therapeutic options for the treatment of NF1 and melanoma.

  5. found that homozygous Stat5 (show STAT5A Antibodies) deficiency extended the lifespan of Nf1-deficient mice and eliminated the development of myeloproliferative neoplasm associated with Nf1 gene loss

  6. summarise current knowledge about genotype-phenotype relationships in NF1 microdeletion patients and discuss the potential role of the genes located within the NF1 microdeletion interval whose haploinsufficiency may contribute to the more severe clinical phenotype

  7. Notch (show NOTCH1 Antibodies) is an Nf1 effector.

  8. the results from our work show that the molecular basis of NF1 splicing mutations is diverse. Therefore, molecular characterization at both the gDNA and mRNA levels allowed for a better understanding of gDNA-mRNA correlations of NF1 mutations.

  9. Results suggest that the Neurofibromatosis 1-Noonan syndrome (NFNS) phenotype may be the result of both a genetic factor of mutation in the neurofibromin 1 gene (NF1) and an epigenetic/environmental factor.

  10. The findings of this study suggest that the most childhood NF1-associated low-grade gliomas are midline and benign in nature, hemispheric NF1-related gliomas may have a more aggressive biological and clinical behavior.

Neurofibromin 1 (NF1) Antigen Profile

Antigen Summary

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Alternative names and synonyms associated with Neurofibromin 1 (NF1)

  • neurofibromin 1 (NF1) antibody
  • Neurofibromin 1 (Nf1) antibody
  • neurofibromin 1a (nf1a) antibody
  • neurofibromin (NF1) antibody
  • neurofibromin (AaeL_AAEL008371) antibody
  • neurofibromin (CpipJ_CPIJ011774) antibody
  • neurofibromin (Smp_148460) antibody
  • neurofibromin (LOC100349438) antibody
  • neurofibromatosis 1 (Nf1) antibody
  • neurofibromin 1 (Nf1) antibody
  • AW494271 antibody
  • CG8318 antibody
  • Dmel\\CG8318 antibody
  • dNF1 antibody
  • E030030H24Rik antibody
  • fe06d03 antibody
  • hm:zehn0874 antibody
  • Nf-1 antibody
  • nf1 antibody
  • NFNS antibody
  • VRNF antibody
  • WSS antibody
  • wu:fe06d03 antibody
  • zehn0874 antibody

Protein level used designations for anti-Neurofibromin 1 (NF1) Antibodies

neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) , CG8318-PB , CG8318-PC , CG8318-PD , CG8318-PE , CG8318-PF , Neurofibromatosis-1 , Nf1-PB , Nf1-PC , Nf1-PD , Nf1-PE , Nf1-PF , neurofibramatosis-1 , neurofibromatosis 1 , neurofibromatosis factor 1 , neurofibromatosis type 1 , neurofibromin , neurofibromin 1 , neurofibromin-like , neurofibromatosis-related protein NF-1 , Neurofibromatosis type 1

100071896 Equus caballus
43149 Drosophila melanogaster
280877 Bos taurus
326708 Danio rerio
454566 Pan troglodytes
493675 Felis catus
531372 Bos taurus
593418 Strongylocentrotus purpuratus
100023872 Monodelphis domestica
100392547 Callithrix jacchus
100482656 Ailuropoda melanoleuca
100546215 Meleagris gallopavo
100603967 Nomascus leucogenys
712911 Macaca mulatta
5570549 Aedes aegypti
6045114 Culex quinquefasciatus
8341839 Schistosoma mansoni
100349438 Oryctolagus cuniculus
18015 Mus musculus
4763 Homo sapiens
24592 Rattus norvegicus
100730274 Cavia porcellus
396085 Gallus gallus
480618 Canis lupus familiaris
100526136 Sus scrofa
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