Browse our anti-CD51 (ITGAV) Antibodies

Full name:
anti-Integrin alpha V Antibodies (ITGAV)
On are 394 Integrin alpha V (ITGAV) Antibodies from 29 different suppliers available. Additionally we are shipping CD51 Proteins (14) and CD51 Kits (12) and many more products for this protein. A total of 426 CD51 products are currently listed.
1110004F14Rik, 2610028E01Rik, Cd51, D430040G12Rik, MSK8, VNRA, VTNR
list all antibodies Gene Name GeneID UniProt
ITGAV 16410 P43406
ITGAV 3685 P06756
ITGAV 296456  

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All available anti-CD51 Antibodies

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Top referenced anti-CD51 Antibodies

  1. Human Polyclonal CD51 Primary Antibody for FACS, IF (p) - ABIN674784 : Mondal, Barui, Chaudhuri: The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor. in Biomaterials 2013 (PubMed)
    Show all 4 references for 674784

  2. Human Polyclonal CD51 Primary Antibody for FACS, ICC - ABIN4900194 : Rhein, Brouillette, Schaack, Chiorini, Maury: Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry. in Journal of virology 2016 (PubMed)
    Show all 3 references for 4900194

  3. Human Monoclonal CD51 Primary Antibody for EIA, IF - ABIN1106450 : Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006 (PubMed)
    Show all 3 references for 1106450

  4. Dog (Canine) Monoclonal CD51 Primary Antibody for IF, WB - ABIN968314 : Bodary, McLean: The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. in The Journal of biological chemistry 1990 (PubMed)
    Show all 3 references for 968314

  5. Chicken Monoclonal CD51 Primary Antibody for FACS, IP - ABIN319776 : Simpson, Horton: Expression of the vitronectin receptor during embryonic development; an immunohistological study of the ontogeny of the osteoclast in the rabbit. in British journal of experimental pathology 1989 (PubMed)
    Show all 3 references for 319776

  6. Human Monoclonal CD51 Primary Antibody for FACS - ABIN4898649 : Chang, Lo, Juan, Chang, Chuang: Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells. in PLoS ONE 2012 (PubMed)
    Show all 2 references for 4898649

  7. Human Monoclonal CD51 Primary Antibody for FACS, IP - ABIN263013 : Grzeszkiewicz, Kirschling, Chen, Lau: CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for 263013

  8. Human Polyclonal CD51 Primary Antibody for IF (p), IHC (p) - ABIN678983 : Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. in Stem cells (Dayton, Ohio) 2016 (PubMed)

More Antibodies against CD51 Interaction Partners

Mouse (Murine) Integrin alpha V (ITGAV) interaction partners

  1. The synergy of circulating factor suPAR and APOL1 (show APOL1 Antibodies) G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD.

  2. Suggest that alphavbeta3 integrin plays an important role in coordinating hepatocyte division during liver regeneration after partial hepatectomy via crosstalk with fibrin ECM (show MMRN1 Antibodies).

  3. Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Antibodies).

  4. This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.

  5. These data support the hypothesis that IL-1beta (show IL1B Antibodies) was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1 (show TGFB1 Antibodies).

  6. Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.

  7. These results suggest that phloretin was an inhibitor of actin podosomes and sealing zone, disrupting alpha5beta3 integrin-c-Src-Pyk2/Syk signaling pathway for the regulation of actin cytoskeletal organization in osteoclasts.

  8. TN-C (show TNC Antibodies) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3/FAK (show PTK2 Antibodies)-Src (show SRC Antibodies)/NF-kappaB (show NFKB1 Antibodies), resulting in increased fibrosis.

  9. Lung histology revealed aberrant elastin (show ELN Antibodies) production and impaired lung septation in oxygen-exposed lungs, while tropoelastin (show ELN Antibodies), integrin alphav, fibulin-1 (show FBLN1 Antibodies), fibulin-2 (show FBLN2 Antibodies) and fibulin-4 (show FBLN4 Antibodies) gene expression were elevated.

  10. Knock-in mice expressing a CCN1 (show CCNA2 Antibodies) mutant that is unable to bind alphavbeta5/alphavbeta3 were impaired in ductular reaction. CCN1 (show CCNA2 Antibodies), acting through its alphav beta3/alphav beta5 binding site, is critical for survival after bile duct ligation.

Human Integrin alpha V (ITGAV) interaction partners

  1. The synergy of circulating factor suPAR and APOL1 (show APOL1 Antibodies) G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD.

  2. overexpression of syndecan-1 confers to B-LCs an increased capacity to migrate in response to Tat, owing to a switch from a CXCR4/G-protein/Rac to a syndecan-1/alphavbeta3/pp60src/pp125FAK signal transduction pathway that depends on the formation of a complex in which syndecan-1 interacts with Tat via its HS-chains, with alphavbeta3 via its core protein ectodomain and with pp60src via its intracellular tail

  3. sPLA2-IIA (show PLA2G2A Antibodies) activates Integrin alphaVbeta3 and Integrin alpha4beta1 in an allosteric manner. (Review)

  4. These results indicate that CD51 is a novel functional marker for colorectal CSCs which may provide an therapeutic target for the efficient elimination of colorectal CSCs.

  5. Data show that dendritic cells (DCs) induced Th17 cell differentiation through miR (show MLXIP Antibodies)-363/Integrin alphav/TGF-beta (show TGFB1 Antibodies) pathway in patients with rheumatoid arthritis (RA).

  6. integrin alphaVbeta6 binds pro-TGF-beta1 (show TGFB1 Antibodies) in an orientation biologically relevant for force-dependent release of TGF-beta (show TGFB1 Antibodies) from latency

  7. In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (show ANGPT2 Antibodies) Ang-1 (show ANGPT1 Antibodies), but not the receptor binding domain of Ang-2 (show ANGPT2 Antibodies), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (show MAPK1 Antibodies) signaling in the presence of both Ang-1 (show ANGPT1 Antibodies) and fibronectin (show FN1 Antibodies)

  8. The findings suggest that, in contrast with previous models, the ligand-binding site of integrin alphaVbeta3, binds to the constant region (helices A and B) of the EC2 (show TCF15 Antibodies) domain of CD9 (show CD9 Antibodies), CD81 (show CD81 Antibodies), and CD151 (show CD151 Antibodies) antigens.

  9. Integrin alphav is required for local activation of latent TGFbeta (show TGFB1 Antibodies), and the wound healing defect in the setting of integrin alphav loss was rescued by exogenous, active TGFbeta (show TGFB1 Antibodies).

  10. Taken together, our findings suggested that HMGB1 (show HMGB1 Antibodies) enhances tumor cell migration ability by activating alphavbeta3/FAK (show PTK2 Antibodies) through TLR4 (show TLR4 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signaling, leading to metastasis of NSCLC.

Pig (Porcine) Integrin alpha V (ITGAV) interaction partners

  1. The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. Inhibition of integrin alphavbeta3 prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin alpha V (ITGAV) interaction partners

  1. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  2. specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.

  3. These results demonstrate the critical role of the RhoA (show RHOA Antibodies)/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.

CD51 (ITGAV) Antigen Profile

Antigen Summary

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with CD51 (ITGAV)

  • integrin, alpha V (ITGAV) antibody
  • integrin alpha V (Itgav) antibody
  • integrin, alpha V (Itgav) antibody
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV) antibody
  • 1110004F14Rik antibody
  • 2610028E01Rik antibody
  • Cd51 antibody
  • D430040G12Rik antibody
  • MSK8 antibody
  • VNRA antibody
  • VTNR antibody

Protein level used designations for ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , alphav integrin , integrin alpha V , integrin alpha-V , vitronectin receptor alpha polypeptide (VNRA) , vitronectin receptor subunit alpha , antigen identified by monoclonal antibody L230 , integrin alphaVbeta3 , Dnmt3l-ps1 pseudogene , alphaV integrin , integrin alpha v , vitronectin receptor alpha subunit , integrin alpha V subunit

100068706 Equus caballus
443143 Ovis aries
16410 Mus musculus
3685 Homo sapiens
296456 Rattus norvegicus
488437 Canis lupus familiaris
397285 Sus scrofa
396420 Gallus gallus
281875 Bos taurus
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