Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) Antibodies:
anti-Rat (Rattus) Antibodies:
Go to our pre-filtered search.
Human Polyclonal ZNF703 Primary Antibody for ELISA, WB - ABIN250795
Garcia, Pole, Chin, Teschendorff, Naderi, Ozdag, Vias, Kranjac, Subkhankulova, Paish, Ellis, Brenton, Edwards, Caldas: A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. in Oncogene 2005
Human Polyclonal ZNF703 Primary Antibody for ICC, IF - ABIN4367532
Holland, Burleigh, Git, Goldgraben, Perez-Mancera, Chin, Hurtado, Bruna, Ali, Greenwood, Dunning, Samarajiwa, Menon, Rueda, Lynch, McKinney, Ellis, Eaves, Carroll, Curtis, Aparicio, Caldas: ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. in EMBO molecular medicine 2011
Results show that ZNF703 is up-regulated in 63.4% of non-small cell lung cancer (NSCLC) tumor samples and it may contribute to tumor development by activating the Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway in NSCLC.
In vitro function assays demonstrated that SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies) cause promotion of cell viability in ESCC cells. Authors further verified that SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies) could also activate the expression of ZNF703 in ESCC cells, which might contribute to the role of SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies) in ESCC cells.
Results show that ZNF703 overexpression is associated with adverse prognosis in head and neck squamous cell carcinomas, which might be a novel biomarker for this type of neoplasm.
ZNF703 was a target of SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies).
Results show that ZNF703 expression is upregulated in colorectal cancer tissues (CRC (show CALR Antibodies)) and is significantly correlated with tumor size, pathological grading, and serosal and lymph node metastasis suggesting that it may act as an oncogene (show RAB1A Antibodies) in CRC (show CALR Antibodies).
The results showed that ZNF703 acts as a gastric cancer oncogene (show RAB1A Antibodies)
High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer.
Data indicate that ZNF703 overexpression in MCF-7 breast cancer cells activated the Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway, downregulated ERalpha (show ESR1 Antibodies), and reduced the antitumor effect of tamoxifen.
The conserved domains are essential for proper subcellular localization and transcriptional repression of the NLZ1/ZNF703 protein.
ZNF703 expression results in the activation of stem cell-related gene expression leading to an increase in cancer stem cells.
Results provide evidence that Zfp703 is a novel feedback suppressor of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling that functions by inhibiting the association of beta-catenin (show CTNNB1 Antibodies) with Tcf1 (show HNF1A Antibodies) on Wnt (show WNT2 Antibodies) response elements in target gene enhancers.
Zeppo1 is a key regulator of breast cancer progression
Nlz1 is required for cilia formation in zebrafish embryogenesis.
nlz1 is expressed in the presumptive hindbrain and midbrain/hindbrain boundary. nlz2 (show ZNF503 Antibodies) is uniquely expressed more anteriorly, in the presumptive midbrain and diencephalon.
Nlz1/Znf703 acts as a repressor of transcription
identify misregulation of pax2 (show PAX2 Antibodies) in the developing eye of morphant fish, suggesting that Nlz1 and Nlz2 (show ZNF503 Antibodies) act upstream of the Pax2 (show PAX2 Antibodies) pathway in directing proper closure of the optic fissure
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.
zinc finger elbow-related proline domain protein 1
, ES neuronal differentiation 2
, nocA related zinc finger 1
, nocA-like zinc finger protein 1
, nocA-related zinc finger protein 1