You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our CDKN1C Proteins (CDKN1C)

Full name:
Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) Proteins (CDKN1C)
On www.antibodies-online.com are 3 Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) Proteins from 2 different suppliers available. Additionally we are shipping CDKN1C Antibodies (151) and CDKN1C Kits (5) and many more products for this protein. A total of 167 CDKN1C products are currently listed.
Synonyms:
AL024410, BWCR, BWS, cb961, CDKI, DFNB48, Kip2, p27Xic1-a, p57, p57(kip2), p57Kip2, USH1J, WBS, zgc:86618
list all proteins Gene Name GeneID UniProt
CDKN1C 10518 O75838
Rat CDKN1C CDKN1C 246060  
CDKN1C 12577 P49919

Show all synonyms

CDKN1C Proteins (CDKN1C) by Origin

Select your origin of interest

More Proteins for CDKN1C Interaction Partners

Human Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) interaction partners

  1. These results indicate that the inhibitory effect of rapamycin may be due mainly to increased p14 (show S100A9 Proteins), p15 (show CDKN2B Proteins), and p57 expression via promoter demethylation and decreased mTOR (show FRAP1 Proteins) and p70S6K (show RPS6KB1 Proteins) expression in ALL cell lines.

  2. Jab1/Csn5 (show COPS5 Proteins) expression with concurrent low p57 expression associated with poor overall survival in hepatocellular carcinoma

  3. We identified a novel variant (rs7164338) on chromosome 15q25.1 in the CIB2 associated with lower pulse wave velocity.

  4. CIB2 (Calcium and Integrin Binding Protein (show CIB1 Proteins) 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic Family

  5. Using human placental samples, we show that the expression of the imprinted gene CDKN1C associates with birth weight

  6. Our data indicated that reduced cytoplasmic p57 expression is associated with hepatocellular carcinoma invasion.

  7. CDKN1C sequencing should be performed for BWS patients presenting with abdominal wall defects or cleft palate without 11p15 methylation defects or body asymmetry, or in familial cases of BWS.

  8. This report shows that p57(Kip2) is a novel target of miR (show MLXIP Proteins)-21 in prostate cancer and revealing a novel oncogenic function of this microRNA.

  9. Data show the presence of maternally derived extra copies of the distal chromosome 11p involving the wild-type cyclin-dependent kinase inhibitor 1C protein (CDKN1C).

  10. downregulation of CDKN1 (show CDKN1A Proteins) by siRNA blocked the activity of miR (show MLXIP Proteins)-25 on promoting glioma cell proliferation.

Zebrafish Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) interaction partners

  1. Myod (show MYOD1 Proteins) in turn up-regulates cdkn1c, thereby providing a positive feedback loop that switches myogenic cells to terminal differentiation

  2. p57Kip2 is both necessary and sufficient to mediate Shh (show SHH Proteins)-induced cell-cycle exit in the deveoping zebrafish retina.

  3. during late embryogenesis, neural cells that have low but functional levels of Cdkn1c, regulated by Notch (show NOTCH1 Proteins) activity, are specified for oligodendrocyte fate

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) interaction partners

  1. Methylation of KvDMR1 involved in regulating the imprinting of CDKN1C

  2. proper expression levels of the imprinted genes CDKN1C and PHLDA2 (show PHLDA2 Proteins) are critical for embryo development

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) interaction partners

  1. indicate that the effects of insulin-like growth factor 2 (IGF2 (show IGF2 Proteins)) are mediated by direct upregulation of the cyclin-dependent kinase inhibitor p57 (p57).

  2. Data show that transforming growth factor beta (TGFbeta (show TGFB1 Proteins))-induced changes in Gata2 transcription factor (show GATA2 Proteins) and cyclin-dependent kinase inhibitor 1C (P57) expression in hematopoietic progenitors are conveyed through Smad (show SMAD1 Proteins) signaling via Smad4 protein (show SMAD4 Proteins).

  3. This study reveals a key requirement for Cdkn1c in the early development of the brown adipose lineages.

  4. Lhx6 (show LHX6 Proteins) and Lhx8 (show LHX8 Proteins) promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2

  5. hepatoblasts in p57(Kip2)-/- mice were highly proliferative and had deficient maturation compared with those in wild-type (WT) mice.

  6. Data indicate that cyclin-dependent kinase inhibitor 1C (P57 was post-transcriptionally regulated by microRNA miR (show MLXIP Proteins)-221 in embryonic stem (ES) cells.

  7. Data show that disruption of potassium voltage-gated channel, KQT-like subfamily Q, member1 (KCNQ1 (show KCNQ1 Proteins)) results in increased expression of cyclin-dependent kinase inhibitor 1C (Cdkn1c) only when the mutation is on the paternal allele.

  8. Results support a model where ARX regulates the expansion of cortical progenitor cells through repression of Cdkn1c

  9. p57 and p21 serve nonredundant functions in trophoblast giant cells; the role of p21 in suppressing apoptosis is restricted to terminally differentiated cells.

  10. In the absence of maintained DNA methylation (show HELLS Proteins) (Dnmt1 (show DNMT1 Proteins)(-/-)), Cdkn1c escapes silencing demonstrating the requirement for DNA methylation (show HELLS Proteins) in long term silencing in vivo.

CDKN1C Protein Profile

Protein Summary

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with CDKN1C

  • calcium and integrin binding family member 2 (CIB2)
  • cyclin-dependent kinase inhibitor 1C (Cdkn1c)
  • cyclin-dependent kinase inhibitor 1C (cdkn1c)
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C)
  • cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c)
  • AL024410 protein
  • BWCR protein
  • BWS protein
  • cb961 protein
  • CDKI protein
  • DFNB48 protein
  • Kip2 protein
  • p27Xic1-a protein
  • p57 protein
  • p57(kip2) protein
  • p57Kip2 protein
  • USH1J protein
  • WBS protein
  • zgc:86618 protein

Protein level used designations for CDKN1C

2810434I23Rik , DNA-dependent protein kinase catalytic subunit-interacting protein 2 , KIP 2 , Usher syndrome 1J (autosomal recessive) , calcium and integrin-binding family member 2 , cyclin-dependent kinase inhibitor 1C, p57 , cyclin-dependent kinase inhibitor p57 , p57KIP2 A3sh , cyclin-dependent kinase inhibitor 1C (p57, Kip2) , p57kip2 , cyclin-dependent kinase inhibitor 1C

GENE ID SPECIES
10518 Homo sapiens
246060 Rattus norvegicus
399483 Danio rerio
1028 Homo sapiens
510972 Bos taurus
12577 Mus musculus
Selected quality suppliers for CDKN1C Proteins (CDKN1C)
Did you look for something else?