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LIN54 harboring a mutation in CHC domain is localized to the cytoplasm and inhibits cell cycle progression.
the cysteine-rich CXC domain of LIN54 is a novel DNA-binding domain that binds to the cdc2 (show CDK1 Proteins) promoter in a sequence-specific manner
LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009
CXC domain containing 1
, CXC domain-containing protein 1
, protein lin-54 homolog